1 University of Copenhagen, Copenhagen, Denmark.
2 Steno Diabetes Center Copenhagen, Gentofte, Denmark.
Diabetes Technol Ther. 2019 Apr;21(4):215-221. doi: 10.1089/dia.2019.0007.
In a 4-month follow-up survey, we examined whether treatment with continuous subcutaneous insulin infusion (CSII) and/or continuous glucose monitoring (CGM) in adults with type 1 diabetes was associated with sustained skin problems and whether skin problems were associated with diabetes-related emotional distress.
A total of 111 adult patients completed a follow-up questionnaire concerning skin problems as a result of CSII and/or CGM use. The questionnaire included a patient-reported outcome measure, the Problem Areas in Diabetes (PAID) scale.
Current visible skin problems caused by CSII or CGM use were reported by 51 (46.0%) participants, in 34 (66.7%) of whom skin problems had been reported more than 4 months earlier. Seventy-two (64.9%) participants reported skin problems as a result of CSII use, whereas 38 (74.5%) reported skin problems owing to CGM use at some time. Itching was the most prevalent complaint. CSII-related itching was associated with a mean PAID score >20 (P = 0.01), and patients with more than one skin problem had an increased PAID score compared with those with one or no skin problems (P = 0.006).
More than half patients treated with CSII, CGM, or both had experienced skin problems during 4 months of follow-up that were associated with increased diabetes burden. Skin problems represent a persistent health issue affecting diabetes-specific emotional distress.
在一项为期 4 个月的随访调查中，我们研究了成人 1 型糖尿病患者接受持续皮下胰岛素输注（CSII）和/或连续血糖监测（CGM）治疗是否与持续的皮肤问题相关，以及皮肤问题是否与糖尿病相关的情绪困扰相关。
共有 111 名成年患者完成了一份关于 CSII 和/或 CGM 使用导致皮肤问题的随访问卷。该问卷包括一个患者报告的结果测量，即糖尿病问题领域（PAID）量表。
51 名（46.0%）参与者报告了目前由 CSII 或 CGM 使用引起的可见皮肤问题，其中 34 名（66.7%）参与者在 4 个月前就报告了皮肤问题。72 名（64.9%）参与者报告了 CSII 使用引起的皮肤问题，而 38 名（74.5%）参与者在某些时候报告了 CGM 使用引起的皮肤问题。瘙痒是最常见的投诉。CSII 相关的瘙痒与平均 PAID 评分>20 相关（P=0.01），且与只有一个或没有皮肤问题的患者相比，有多个皮肤问题的患者的 PAID 评分更高（P=0.006）。
在 4 个月的随访期间，超过一半接受 CSII、CGM 或两者治疗的患者经历了与糖尿病负担增加相关的皮肤问题。皮肤问题是一个持续存在的健康问题，会影响糖尿病相关的情绪困扰。
