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人工细胞发展成为纳米医学、生物治疗学、血液代用品、药物输送、酶/基因治疗、癌症治疗、细胞/干细胞治疗、纳米粒子、脂质体、生物包封、复制合成细胞、细胞包封/支架、生物吸附剂/免疫吸附剂血液灌流/血浆置换、再生医学、包封微生物、纳米生物技术、纳米技术。

ARTIFICIAL CELL evolves into nanomedicine, biotherapeutics, blood substitutes, drug delivery, enzyme/gene therapy, cancer therapy, cell/stem cell therapy, nanoparticles, liposomes, bioencapsulation, replicating synthetic cells, cell encapsulation/scaffold, biosorbent/immunosorbent haemoperfusion/plasmapheresis, regenerative medicine, encapsulated microbe, nanobiotechnology, nanotechnology.

机构信息

a Artificial Cells and Organs Research Centre, Departments of Physiology, Medicine and Biomedical Engineering, Faculty of Medicine , McGill University , Montreal , Quebec , Canada.

出版信息

Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):997-1013. doi: 10.1080/21691401.2019.1577885.

DOI:10.1080/21691401.2019.1577885
PMID:30945957
Abstract

It is only in the last 20 years that many of the original ideas on artificial cells are being increasingly applied and extended by researchers around the world. Artificial cell has now evolved into nanomedicine, biotherapeutics, blood substitutes, drug delivery, enzyme/gene therapy, cancer therapy, cell/stem cell therapy, nanoparticles, liposomes, bioencapsulation, replicating synthetic cells, cell encapsulation/scaffold, biosorbent/immunosorbent haemoperfusion/plasmapheresis, regenerative medicine, encapsulated microbe, nanobiotechnology, nanotechnology and other areas. More futuristic research includes nanorobot, nanocomputer, multimodal locomotion delivery robot and others. This review starts with a general overview followed by specific examples in more details.

摘要

直到最近 20 年,世界各地的研究人员才开始越来越多地应用和扩展最初关于人工细胞的许多想法。人工细胞现已发展成纳米医学、生物疗法、血液替代品、药物输送、酶/基因治疗、癌症治疗、细胞/干细胞治疗、纳米粒子、脂质体、生物封装、复制合成细胞、细胞封装/支架、生物吸附剂/免疫吸附剂血液灌流/血浆置换、再生医学、包封微生物、纳米生物技术、纳米技术和其他领域。更具未来感的研究包括纳米机器人、纳米计算机、多模态运动输送机器人等。本综述首先概述,然后更详细地介绍具体示例。

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