1 Social and Behavioral Research Branch, National Human Genome Research Institute, Bethesda, MD.
2 Department of Psychology, Columbia University, New York, NY.
Child Obes. 2019 Jul;15(5):289-297. doi: 10.1089/chi.2018.0315. Epub 2019 Apr 4.
Future integration of genomics into weight management may target children with overweight given prospects for prevention. Meanwhile, parents learn about weight-related genomics primarily through the media, and little is known about parental reactions to complex genomic and environmental causes underlying children's obesity risk. Three hundred twenty-four parents with overweight who have a child 3-13 years of age were recruited through Amazon Mechanical Turk. Parents were randomized to read an article highlighting one of three causes of obesity risk: genetics only, family environment only, gene-family environment interactions (G × FE), or read a control article. Parents who perceived their child to be overweight exhibited increased risk perception and guilt over parents of lean children overall, but exhibited decreased worry in response to the G × FE message. Furthermore, parents of children with overweight who received the G × FE message did not exhibit heightened risk perception or guilt, reported that the message was less relevant, and that they paid less attention to it. Multifactorial causal information about children's obesity risk elicits unintended consequences among parents whose children are most at-risk for obesity in adulthood. As these messages are most accurate, it is crucial to investigate effective ways to communicate the holistic nature of obesity risk to parents.
未来,将基因组学纳入体重管理可能会针对超重的儿童,因为有预防的前景。与此同时,父母主要通过媒体了解与体重相关的基因组学知识,而对于导致儿童肥胖风险的复杂基因组和环境因素,父母的反应则知之甚少。通过亚马逊土耳其机器人(Amazon Mechanical Turk),我们招募了 324 名超重的父母,他们的孩子年龄在 3 到 13 岁之间。父母被随机分配阅读一篇强调肥胖风险的三个原因之一的文章:仅遗传、仅家庭环境、遗传-家庭环境相互作用(G×FE),或阅读对照文章。总体而言,与瘦小孩的父母相比,认为自己孩子超重的父母会增加对风险的感知和对父母的内疚感,但对 G×FE 信息的担忧会减少。此外,对于收到 G×FE 信息的超重儿童的父母,他们没有表现出更高的风险感知或内疚感,反而报告说该信息不太相关,并且他们不太关注它。关于儿童肥胖风险的多因素因果信息会给那些孩子在成年后患肥胖风险最高的父母带来意想不到的后果。由于这些信息是最准确的,因此,研究向父母传达肥胖风险整体性质的有效方法至关重要。