Department of Hepatology, First Hospital of Jilin University, Jilin University, Changchun 130021, Jilin Province, China.
World J Gastroenterol. 2019 Mar 28;25(12):1445-1456. doi: 10.3748/wjg.v25.i12.1445.
Explosive economic growth and increasing social openness in China over the last 30 years have significantly boosted alcohol consumption, and consequently, the incidence of alcoholic liver disease (ALD) in China has increased. Because the epidemiologic and clinical features of ALD in the Chinese population may differ from those of the Caucasian population, this review describes the epidemiology, pathogenesis, genetic polymorphisms, diagnosis, and treatment of ALD in the Chinese population. This updated knowledge of ALD in China provides information needed for a global understanding of ALD and may help in the development of useful strategies for reducing the global ALD burden.
过去 30 年来，中国经济的爆炸式增长和社会的日益开放极大地促进了酒精消费，由此导致中国的酒精性肝病（ALD）发病率上升。由于中国人群的 ALD 的流行病学和临床特征可能与白种人群不同，因此本综述描述了中国人群的 ALD 的流行病学、发病机制、遗传多态性、诊断和治疗。中国人群 ALD 的这些最新知识提供了对 ALD 进行全球理解所需的信息，并可能有助于制定有用的策略来减轻全球 ALD 负担。
