Asgharvahedi Farnoosh, Gholizadeh Leila, Siabani Soraya
Faculty of Health, University of Technology Sydney , Ultimo , New South Wales , Australia.
School of Public Health, Kermanshah University of Medical Sciences, Kermanshah , Iran.
Health Care Women Int. 2019 Oct;40(10):1117-1131. doi: 10.1080/07399332.2019.1566332. Epub 2019 Apr 5.
Cardiovascular disease (CVD) remains the main cause of morbidity and mortality in women worldwide. Apart from the well-established risk factors, some adverse pregnancy outcomes have been found to be associated with increased risk of CVD in women. We reviewed the literature on the risk of CVD in women with a history of pregnancy loss (miscarriage and/or stillbirth). Electronic databases including MEDLINE and CINAHL were searched for English language articles published from 2000 to July 2016. Following the application of study inclusion and exclusion criteria, we selected seven studies for review. Women with history of miscarriage and/or stillbirth are more likely to develop coronary heart disease (CHD), but not stroke in their later life compared with women without these conditions. The risk is particularly greater in women with multiple miscarriages or stillbirths. Health professionals should be aware of the risk associated with miscarriage and stillbirth, and use maternal history to identify, refer, closely monitor, and engage these high risk women in healthy lifestyle and risk factor modification programs.
心血管疾病（CVD）仍然是全球女性发病和死亡的主要原因。除了已明确的危险因素外，一些不良妊娠结局也被发现与女性患心血管疾病的风险增加有关。我们回顾了关于有流产（包括流产和/或死产）史的女性患心血管疾病风险的文献。通过检索包括MEDLINE和CINAHL在内的电子数据库，查找2000年至2016年7月发表的英文文章。在应用研究纳入和排除标准后，我们选择了七项研究进行综述。与没有这些情况的女性相比，有流产和/或死产史的女性在晚年更易患冠心病（CHD），但不易患中风。多次流产或死产的女性风险尤其更高。卫生专业人员应意识到与流产和死产相关的风险，并利用孕产史来识别、转诊、密切监测这些高危女性，让她们参与健康生活方式和风险因素改善项目。
