CICECO - Aveiro Institute of Materials, Universidade de Aveiro, Campus de Santiago, 3810-193 Aveiro, Portugal; QOPNA & LAQV/REQUIMTE, Departamento de Química, Universidade de Aveiro, Campus de Santiago, 3810-193 Aveiro, Portugal.
QOPNA & LAQV/REQUIMTE, Departamento de Química, Universidade de Aveiro, Campus de Santiago, 3810-193 Aveiro, Portugal.
Int J Biol Macromol. 2019 Jul 15;133:235-242. doi: 10.1016/j.ijbiomac.2019.04.021. Epub 2019 Apr 4.
Marine environments are an enormous source of materials with biological interest, such as sulphated polysaccharides, which have relevant biological activities. In this study the potential of salt pan brine water as an easily accessible source of sulphated polysaccharides was evaluated. This water revealed to have a high quantity of polymeric material, five times more than sea water, mainly composed by highly sulphated polysaccharides. Structural analysis identified a diversity of polysaccharides, namely rhamnans, fucans, mannans, xylomannans, glucuronomannans, galactans, and glucans. All these structures seem to form complexes that are resistant to the salt pan conditions along salt production. These polysaccharides showed in vitro stimulatory activity for B cells, suggesting their potential application in nutraceutical and biomedical fields. Salt pan brine water is a valuable source of environmentally friendly and low-cost available bioactive compounds prone to be exploited.
海洋环境是具有生物活性的物质的巨大来源，如硫酸多糖，具有相关的生物活性。在这项研究中，评估了盐田卤水作为一种易于获取的硫酸多糖来源的潜力。这种水显示出高分子量物质的高含量，比海水多五倍，主要由高度硫酸化的多糖组成。结构分析确定了多种多糖，即鼠李聚糖、岩藻聚糖、甘露聚糖、木聚糖、葡萄糖醛酸甘露聚糖、半乳糖和葡聚糖。所有这些结构似乎都形成了复合物，能够抵抗盐田条件下的盐分生产。这些多糖在体外对 B 细胞具有刺激活性，表明它们在营养保健品和生物医学领域有潜在的应用。盐田卤水是一种有价值的环保、低成本、可用生物活性化合物的来源，很容易被开发利用。
