Stimulatory role of exosomes in the context of therapeutic anti-cancer vaccines.
作者信息
Whiteside Theresa L
机构信息
University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA.
出版信息
Biotarget. 2017 May;1. doi: 10.21037/biotarget.2017.05.05. Epub 2017 May 25.
Abstract
摘要
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本文引用的文献
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Human tumor-derived exosomes (TEX) regulate Treg functions via cell surface signaling rather than uptake mechanisms.人肿瘤来源的外泌体（TEX）通过细胞表面信号传导而非摄取机制调节调节性T细胞（Treg）的功能。
Oncoimmunology. 2017 Jul 19;6(8):e1261243. doi: 10.1080/2162402X.2016.1261243. eCollection 2017.
2
Exosomes carrying immunoinhibitory proteins and their role in cancer.携带免疫抑制蛋白的外泌体及其在癌症中的作用。
Clin Exp Immunol. 2017 Sep;189(3):259-267. doi: 10.1111/cei.12974. Epub 2017 May 19.
3
Exosomes from M1-Polarized Macrophages Potentiate the Cancer Vaccine by Creating a Pro-inflammatory Microenvironment in the Lymph Node.M1极化巨噬细胞来源的外泌体通过在淋巴结中创造促炎微环境增强癌症疫苗效果。
Mol Ther. 2017 Jul 5;25(7):1665-1675. doi: 10.1016/j.ymthe.2017.02.007. Epub 2017 Mar 9.
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Emerging Opportunities and Challenges in Cancer Immunotherapy.癌症免疫疗法中的新机遇与挑战
Clin Cancer Res. 2016 Apr 15;22(8):1845-55. doi: 10.1158/1078-0432.CCR-16-0049.
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Introduction to Extracellular Vesicles: Biogenesis, RNA Cargo Selection, Content, Release, and Uptake.细胞外囊泡简介：生物发生、RNA 货物选择、内容物、释放和摄取
Cell Mol Neurobiol. 2016 Apr;36(3):301-12. doi: 10.1007/s10571-016-0366-z. Epub 2016 Apr 6.
6
Dendritic cell-derived exosomes for cancer therapy.用于癌症治疗的树突状细胞衍生外泌体。
J Clin Invest. 2016 Apr 1;126(4):1224-32. doi: 10.1172/JCI81137.
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Exosomes and tumor-mediated immune suppression.外泌体与肿瘤介导的免疫抑制。
J Clin Invest. 2016 Apr 1;126(4):1216-23. doi: 10.1172/JCI81136. Epub 2016 Feb 29.
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The potential of tumor-derived exosomes for noninvasive cancer monitoring.肿瘤来源外泌体在无创癌症监测中的潜力。
Expert Rev Mol Diagn. 2015;15(10):1293-310. doi: 10.1586/14737159.2015.1071666. Epub 2015 Aug 2.
9
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Improved vaccine efficacy of tumor exosome compared to tumor lysate loaded dendritic cells in mice.与负载肿瘤裂解物的树突状细胞相比，肿瘤外泌体增强了疫苗在小鼠中的疗效。
Int J Cancer. 2015 Feb 15;136(4):E74-84. doi: 10.1002/ijc.29100. Epub 2014 Aug 5.
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