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碱性戊二醛溶液对多种非典型分枝杆菌的杀菌活性。

Bactericidal activity of alkaline glutaraldehyde solution against a number of atypical mycobacterial species.

作者信息

Collins F M

出版信息

J Appl Bacteriol. 1986 Sep;61(3):247-51. doi: 10.1111/j.1365-2672.1986.tb04283.x.

DOI:10.1111/j.1365-2672.1986.tb04283.x
PMID:3096931
Abstract

The mycobactericidal activity of 2% alkaline glutaraldehyde solution was determined using standardized suspensions of 10 species of atypical mycobacteria and compared with that for virulent Mycobacterium tuberculosis. Suspensions of M. avium, M. intracellulare and M. gordonae were more resistant to disinfection by the glutaraldehyde than were virulent tubercle bacilli while M. kansasii, M. scrofulaceum and M. szulgae were somewhat more susceptible. Mycobacterium marinum, M. smegmatis and M. fortuitum were highly sensitive to the disinfectant action of the alkaline glutaraldehyde solution. This variation in sensitivity shown by apparently closely related strains of mycobacteria to this disinfectant has important practical implications.

摘要

使用10种非典型分枝杆菌的标准化悬液测定了2%碱性戊二醛溶液的杀分枝杆菌活性,并与强毒结核分枝杆菌的杀分枝杆菌活性进行了比较。鸟分枝杆菌、胞内分枝杆菌和戈登分枝杆菌的悬液对戊二醛消毒的抗性比强毒结核杆菌更强,而堪萨斯分枝杆菌、瘰疬分枝杆菌和苏尔加分枝杆菌则稍易被戊二醛杀灭。海分枝杆菌、耻垢分枝杆菌和偶然分枝杆菌对碱性戊二醛溶液的消毒作用高度敏感。明显密切相关的分枝杆菌菌株对这种消毒剂表现出的敏感性差异具有重要的实际意义。

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