通过拉曼散射对麻醉气体和呼吸气体进行专门监测。

Dedicated monitoring of anesthetic and respiratory gases by Raman scattering.

作者信息

VanWagenen R A, Westenskow D R, Benner R E, Gregonis D E, Coleman D L

出版信息

J Clin Monit. 1986 Oct;2(4):215-22. doi: 10.1007/BF02851168.

Abstract

The monitoring of respiratory and anesthetic gases in the operating room is important for patient safety. This study measured the accuracy and response time of a multiple-gas monitoring instrument that uses Raman light scattering. Measurements of oxygen, carbon dioxide, nitrogen, nitrous oxide, halothane, enflurane, and isoflurane concentrations were compared with a gas mixer standard and with measurements made with an infrared anesthetic agent analyzer. Correlation coefficients were all greater than 0.999, and probable errors were less than 0.43 vol% for the gases and less than 0.03 vol% for the volatile anesthetics. Response time was 67 ms with a sample flow rate of 150 ml/min. There was some signal overlap between nitrogen and nitrous oxide and between the volatile anesthetic agents. Such overlap can be compensated for by linear matrix analysis. The Raman instrument promises a monitoring capability equivalent to the mass spectrometer and should prove attractive for the monitoring of respiratory and anesthetic gases in the operating room.

摘要

手术室中对呼吸气体和麻醉气体进行监测对患者安全至关重要。本研究测量了一种采用拉曼光散射的多气体监测仪器的准确性和响应时间。将氧气、二氧化碳、氮气、一氧化二氮、氟烷、恩氟烷和异氟烷浓度的测量结果与气体混合器标准进行了比较，并与使用红外麻醉剂分析仪进行的测量结果进行了比较。相关系数均大于0.999，气体的可能误差小于0.43体积%，挥发性麻醉剂的可能误差小于0.03体积%。在样品流速为150 ml/min时，响应时间为67 ms。氮气与一氧化二氮之间以及挥发性麻醉剂之间存在一些信号重叠。这种重叠可以通过线性矩阵分析来补偿。拉曼仪器有望具备与质谱仪相当的监测能力，并且在手术室呼吸气体和麻醉气体监测方面应具有吸引力。