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基于支持向量机的 CT 图像肺部结节检测框架。

Lungs nodule detection framework from computed tomography images using support vector machine.

机构信息

Department of Computer Science, Shaheed Zulfikar Ali Bhutto Institute of Science and Technology, Islamabad, Pakistan.

Department of Software Engineering, Foundation University, Islamabad, Pakistan.

出版信息

Microsc Res Tech. 2019 Aug;82(8):1256-1266. doi: 10.1002/jemt.23275. Epub 2019 Apr 11.

DOI:10.1002/jemt.23275
PMID:30974031
Abstract

The emergence of cloud infrastructure has the potential to provide significant benefits in a variety of areas in the medical imaging field. The driving force behind the extensive use of cloud infrastructure for medical image processing is the exponential increase in the size of computed tomography (CT) and magnetic resonance imaging (MRI) data. The size of a single CT/MRI image has increased manifold since the inception of these imagery techniques. This demand for the introduction of effective and efficient frameworks for extracting relevant and most suitable information (features) from these sizeable images. As early detection of lungs cancer can significantly increase the chances of survival of a lung scanner patient, an effective and efficient nodule detection system can play a vital role. In this article, we have proposed a novel classification framework for lungs nodule classification with less false positive rates (FPRs), high accuracy, sensitivity rate, less computationally expensive and uses a small set of features while preserving edge and texture information. The proposed framework comprises multiple phases that include image contrast enhancement, segmentation, feature extraction, followed by an employment of these features for training and testing of a selected classifier. Image preprocessing and feature selection being the primary steps-playing their vital role in achieving improved classification accuracy. We have empirically tested the efficacy of our technique by utilizing the well-known Lungs Image Consortium Database dataset. The results prove that the technique is highly effective for reducing FPRs with an impressive sensitivity rate of 97.45%.

摘要

云基础设施的出现有可能在医学成像领域的多个领域提供重大利益。云基础设施在医学图像处理中广泛使用的驱动力是计算机断层扫描(CT)和磁共振成像(MRI)数据的大小呈指数级增长。自这些成像技术出现以来,单个 CT/MRI 图像的大小已经增加了很多倍。因此,需要引入有效的和高效的框架,以便从这些大容量图像中提取相关和最合适的信息(特征)。由于早期检测肺癌可以大大提高肺癌扫描仪患者的生存机会,因此有效的和高效的结节检测系统可以发挥至关重要的作用。在本文中,我们提出了一种新的分类框架,用于具有较低假阳性率(FPR),高准确率,高灵敏度,计算成本较低且使用少量特征同时保留边缘和纹理信息的肺部结节分类。所提出的框架包括多个阶段,包括图像对比度增强,分割,特征提取,然后使用这些特征对选定的分类器进行训练和测试。图像预处理和特征选择是主要步骤,在实现改进的分类准确性方面发挥着至关重要的作用。我们通过利用著名的肺部图像联合会数据库数据集来经验性地测试了我们的技术的功效。结果证明,该技术在降低 FPR 方面非常有效,其灵敏度率达到了令人印象深刻的 97.45%。

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