Ammirati M, Cozzens J, Eller T, Ciric I, Tarkington J, Rabin E
Neurosurgery. 1986 Nov;19(5):732-4. doi: 10.1227/00006123-198611000-00003.
Aneurysms were induced in the rat common carotid artery by using the milliwatt carbon dioxide laser to weld an adventitia patch over a hole. This technique proved to be effective and reliable as demonstrated by the 100% incidence of aneurysm formation at the patch site in 28 rats killed 1 week or later after the procedure. It is suggested that this technique may be used to produce intracranial aneurysms in experimental animals due to the minimal vessel manipulation required.
通过使用毫瓦二氧化碳激光在大鼠颈总动脉的一个洞上焊接外膜补片来诱导动脉瘤形成。在手术后1周或更晚处死的28只大鼠中,补片部位动脉瘤形成的发生率为100%,这证明该技术是有效且可靠的。由于所需的血管操作极少,建议该技术可用于在实验动物中产生颅内动脉瘤。