Academic Department of Trauma & Orthopaedics, School of Medicine, University of Leeds, Clarendon Wing, Floor D, Great George Street, Leeds General Infirmary, Leeds, LS1 3EX, UK.
J Orthop Traumatol. 2019 Apr 11;20(1):21. doi: 10.1186/s10195-019-0528-0.
Long bone non-union continues to be a significant worldwide problem. Since its inception over a decade ago, the 'diamond concept', a conceptual framework of what is essential for a successful bone healing response, has gained great acceptance for assessing and planning the management of fracture non-unions. Herein, we discuss the epidemiology of non-unions, the basic science of bone healing in the context of the diamond concept, the currently available results and areas for future research.
长骨骨不连仍然是一个全球性的重大问题。自十多年前提出以来，“钻石概念”作为评估和规划骨折不连管理的概念框架，已经得到了广泛的认可，它包含了成功骨愈合反应所必需的要素。本文讨论了骨不连的流行病学，以及钻石概念背景下的骨愈合基础科学，目前的研究结果和未来研究领域。
