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根据年龄和基础皮质醇水平预测正常志愿者对地塞米松的皮质醇反应:一项阴性研究。

Prediction of cortisol response to dexamethasone from age and basal cortisol in normal volunteers: a negative study.

作者信息

Ansseau M, von Frenckell R, Simon C, Sulon J, Demey-Ponsart E, Franck G

出版信息

Psychopharmacology (Berl). 1986;90(2):276-7. doi: 10.1007/BF00181258.

DOI:10.1007/BF00181258
PMID:3097712
Abstract

The dexamethasone suppression test (1 mg at 23 h and 4 P.M. blood collection) was performed in 22 normal subjects. In contrast to a previous study using 0.5 mg dexamethasone and a 8-9 A.M. post-dexamethasone blood sample, age and basal cortisol level did not significantly predict postdexamethasone cortisol levels.

摘要

对22名正常受试者进行了地塞米松抑制试验(晚上11点服用1毫克地塞米松,并于下午4点采集血样)。与之前使用0.5毫克地塞米松并于上午8 - 9点采集地塞米松给药后血样的研究不同,年龄和基础皮质醇水平并不能显著预测地塞米松给药后的皮质醇水平。

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Prediction of cortisol response to dexamethasone from age and basal cortisol in normal volunteers: a negative study.根据年龄和基础皮质醇水平预测正常志愿者对地塞米松的皮质醇反应:一项阴性研究。
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本文引用的文献

1
A specific laboratory test for the diagnosis of melancholia. Standardization, validation, and clinical utility.一项用于诊断忧郁症的特定实验室检测。标准化、验证及临床效用。
Arch Gen Psychiatry. 1981 Jan;38(1):15-22. doi: 10.1001/archpsyc.1981.01780260017001.
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Cortisol secretion and dexamethasone response in depression.抑郁症中的皮质醇分泌与地塞米松反应
Am J Psychiatry. 1981 Sep;138(9):1218-21. doi: 10.1176/ajp.138.9.1218.
3
Cortisol secretion in relation to age in major depression.重度抑郁症中皮质醇分泌与年龄的关系。
Psychosom Med. 1981 Jun;43(3):235-42. doi: 10.1097/00006842-198106000-00005.
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The dexamethasone suppression test for melancholia.
Br J Psychiatry. 1982 Mar;140:292-304. doi: 10.1192/bjp.140.3.292.
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The dexamethasone suppression test in an elderly population.
Biol Psychiatry. 1981 Dec;16(12):1177-84.
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The dexamethasone suppression test in depressive illness: clinical correlates.抑郁症中的地塞米松抑制试验:临床关联
Psychoneuroendocrinology. 1982;7(4):295-301. doi: 10.1016/0306-4530(82)90033-6.
7
Age and the dexamethasone suppression test in depression.年龄与抑郁症中的地塞米松抑制试验
Am J Psychiatry. 1984 Jul;141(7):872-4. doi: 10.1176/ajp.141.7.872.
8
Mean 14.00-17.00 h plasma cortisol concentration and its relationship to the 1 mg-dexamethasone suppression response in depressives and controls.抑郁症患者和对照组在14.00 - 17.00时的平均血浆皮质醇浓度及其与1毫克地塞米松抑制反应的关系。
Acta Psychiatr Scand. 1984 May;69(5):383-90. doi: 10.1111/j.1600-0447.1984.tb02509.x.
9
Prediction of serum cortisol response to dexamethasone in normal volunteers: a multivariate approach.正常志愿者中地塞米松血清皮质醇反应的预测:一种多变量方法。
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10
Pretreatment DST and hypothalamic-pituitary-adrenocortical function in depressed patients and comparison groups. A multicenter study.抑郁症患者及对照组的治疗前地塞米松抑制试验与下丘脑-垂体-肾上腺皮质功能:一项多中心研究
Arch Gen Psychiatry. 1984 Mar;41(3):257-67. doi: 10.1001/archpsyc.1984.01790140047006.