Yonsei Star Skin & Laser Clinic, Seoul, South Korea.
Department of Dermatology, Chung-Ang University College of Medicine, Seoul, South Korea.
Dermatol Ther. 2019 Jul;32(4):e12922. doi: 10.1111/dth.12922. Epub 2019 Apr 25.
Periorbital hyperpigmentation (POH) is a common condition encountered in dermatology practice. POH is caused by various exogenous and endogenous factors including excessive pigmentation, postinflammatory hyperpigmentation (PIH) secondary to eczema, periorbital edema, excessive vascularity, and aging. Recently, we have experienced several patients who complained of POH with an unusual pattern. Their pigmented lesions had several features in common. The pigmentation occurred bilaterally after aesthetic surgery involving the periorbital region. Periorbital post-purpuric darkness should be distinguished from common POH. Practitioners should ask patients about history of prior aesthetic surgery and make their patients aware that the dark colors are composed of various pigments such as hemosiderin, which make treatment troublesome. Conservative management with expectations for gradual spontaneous regression or laser therapy with multiple wavelengths including 1,064-nm laser for PIH and 650 or 694-nm laser targeting heme-derived pigments may be considered as treatment options.
眶周色素沉着（POH）是皮肤科实践中常见的病症。POH 是由各种外源性和内源性因素引起的，包括过度色素沉着、湿疹引起的炎症后色素沉着（PIH）、眶周水肿、过度血管生成和衰老。最近，我们遇到了几位抱怨眶周色素沉着异常模式的患者。他们的色素沉着病变有几个共同的特征。这些色素沉着发生在涉及眶周区域的美容手术后的双侧。眶周紫癜后暗应与常见的 POH 相区别。从业者应询问患者既往美容手术史，并让患者了解到这些深色由各种色素组成，如含铁血黄素，这使得治疗变得棘手。可考虑保守治疗，期望色素逐渐自发消退，或采用多波长激光治疗，包括针对 PIH 的 1064nm 激光和针对血红素衍生色素的 650 或 694nm 激光。
