National Skin Center, Singapore.
Dermatol Surg. 2011 Sep;37(9):1297-303. doi: 10.1111/j.1524-4725.2011.02065.x. Epub 2011 Jun 17.
Periorbital hyperpigmentation (POH) presents with a dark area surrounding the eyelids. It is an ill-defined condition, and the pathogenesis can be multifactorial.
This epidemiologic study was conducted to assess the prevalence of periorbital hyperpigmentation in Singapore in an attempt to propose a classification.
One thousand consecutive patients attending the general dermatology clinic at the National Skin Center were enrolled in the study to assess for POH, of whom 200 with POH were examined and investigated to define the cause of POH. The possible causes were determined according to a detailed history, clinical examination, and assessment by three dermatologists. The extent of the POH was measured using a mexameter.
The commonest form of POH was the vascular type (41.8%), followed by constitutional (38.6%), postinflammatory hyperpigmentation (12%), and shadow effects (11.4%). The vascular type was seen predominantly in Chinese, whereas as the constitutional type was most common in Indians and Malays.
The vascular form of POH was the predominant type. We propose a comprehensive classification for POH that we hope will influence the choice of treatment modalities used in managing POH in the future.
眶周色素沉着（POH）表现为眼睑周围出现暗区。这是一种定义不明确的病症，其发病机制可能是多因素的。
本研究旨在评估新加坡眶周色素沉着的流行情况，并尝试提出一种分类方法。
本研究共纳入了 1000 例在国家皮肤中心皮肤科就诊的连续患者，以评估 POH 的患病率，其中 200 例 POH 患者接受了检查和调查以确定 POH 的病因。根据详细的病史、临床检查和三位皮肤科医生的评估来确定可能的病因。使用 mexameter 测量 POH 的范围。
最常见的 POH 类型是血管型（41.8%），其次是体质型（38.6%）、炎症后色素沉着（12%）和阴影效应（11.4%）。血管型主要见于华人，而体质型则最常见于印度人和马来人。
血管型 POH 是主要类型。我们提出了一种全面的 POH 分类方法，希望这将影响未来管理 POH 治疗方法的选择。
