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天然来源的牛羟基磷灰石(Cerabone™)联合富血小板纤维蛋白基质用于牙槽窝保存的有效性:一项随机对照临床试验。

Effectiveness of naturally derived bovine hydroxyapatite (Cerabone™) combined with platelet-rich fibrin matrix in socket preservation: A randomized controlled clinical trial.

作者信息

Kollati Prathyusha, Koneru Suneetha, Dwarakanath Chinni Doraswamy, Gottumukkala Sruthima Naga Venkata Satya

机构信息

Department of Periodontics, Vishnu Dental College, Bhimavaram, Andhra Pradesh, India.

出版信息

J Indian Soc Periodontol. 2019 Mar-Apr;23(2):145-151. doi: 10.4103/jisp.jisp_400_18.

DOI:10.4103/jisp.jisp_400_18
PMID:30983786
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6434722/
Abstract

BACKGROUND AND OBJECTIVES

Socket preservation is the procedure which is carried out at the time of extraction to enhance the esthetic predictability of prosthesis and to reduce the number of surgical interventions by minimizing the crestal bone loss. The aim of the present study was to compare the efficacy of natural bovine hydroxyapatite and platelet-rich fibrin (PRF) matrix along with collagen plug to unassisted natural healing in extraction sites.

MATERIALS AND METHODS

A sample of 25 patients of age 17-50 years who require extraction of at least two teeth which were not adjacent to each other were included in the study. One site in each patient was subjected to ridge preservation procedure using Cerabone™ PRF along with collagen plug and the other site was subjected to atraumatic extraction alone. Parameters such as loss of ridge width and loss of ridge height were measured clinically and radiographically at baseline and after 6 months.

RESULTS

The mean loss of width was found to be 2.75 mm (2.75 ± 1.49) at the control site compared to 1.47 mm (1.47 ± 1.44) at the test site. The test site showed 2.31 mm bone fill, (8.7%) compared to the control site.

CONCLUSION

Within the limitations of the study, the results suggest that socket preservation procedure is a reliable method that minimizes the alveolar bone loss.

摘要

背景与目的

牙槽窝保存是在拔牙时进行的一种操作,旨在通过减少牙槽嵴顶骨吸收来提高义齿的美学可预测性,并减少手术干预的次数。本研究的目的是比较天然牛羟基磷灰石和富血小板纤维蛋白(PRF)基质联合胶原塞与拔牙窝自然愈合的效果。

材料与方法

本研究纳入了25例年龄在17至50岁之间、需要拔除至少两颗不相邻牙齿的患者。每位患者的一个拔牙位点采用Cerabone™ PRF联合胶原塞进行牙槽嵴保存操作,另一个位点仅进行无创拔牙。在基线和6个月后,通过临床和影像学测量牙槽嵴宽度减少量和牙槽嵴高度减少量等参数。

结果

对照组位点的平均宽度减少量为2.75 mm(2.75±1.49),而试验组位点为1.47 mm(1.47±1.44)。试验组位点有2.31 mm的骨填充(8.7%),而对照组位点则没有。

结论

在本研究的局限性范围内,结果表明牙槽窝保存操作是一种可靠的方法,可最大程度减少牙槽骨吸收。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24c4/6434722/fb9fde0b3887/JISP-23-145-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24c4/6434722/7102ee23bf65/JISP-23-145-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24c4/6434722/2d05bd046625/JISP-23-145-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24c4/6434722/41eecba050e7/JISP-23-145-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24c4/6434722/ecbb42da49ea/JISP-23-145-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24c4/6434722/7c85337fbaf1/JISP-23-145-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24c4/6434722/fb9fde0b3887/JISP-23-145-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24c4/6434722/7102ee23bf65/JISP-23-145-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24c4/6434722/2d05bd046625/JISP-23-145-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24c4/6434722/41eecba050e7/JISP-23-145-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24c4/6434722/ecbb42da49ea/JISP-23-145-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24c4/6434722/7c85337fbaf1/JISP-23-145-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24c4/6434722/fb9fde0b3887/JISP-23-145-g006.jpg

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