Zhang Chen-Hui, Ma Kun, Yuan Bo-Chao, Yuan Yuan, Chen Yan-Xia
Beijing University of Chinese Medicine Beijing 100029,China.
Xiyuan Hosptial,China Academy of Chinese Medicine Sciences Beijing 100091,China.
Zhongguo Zhong Yao Za Zhi. 2019 Mar;44(6):1087-1093. doi: 10.19540/j.cnki.cjcmm.20190125.001.
The clinical efficacy of Bushen Huoxue traditional Chinese medicine( TCM) in the treatment of hyperprolactinemia were systematically evaluated,which provided evidence-based medical evidence for the treatment of hyperprolactinemia with Bushen Huoxue traditional Chinese medicine. The randomized controlled trials on the treatment of hyperprolactinemia with Bushen Huoxue traditional Chinese medicine were comprehensively searched by computer in PubMed,EMbase,Cochrane Library,CNKI,Wan Fang,VIP,CBM and Meta-analysis was performed. The search time is from the time of self-built database to September 28,2018. A total of 816 patients with hyperprolactinemia met the inclusion criteria in 13 clinical studies. The results of Meta-analysis showed that compared with Western medicines,traditional Chinese medicine for tonifying kidney and activating blood circulation had a comparable effect in reducing prolactin and treating infertility,and had obvious advantages in improving of TCM syndromes,disease recurrence and reducing of side effects.
系统评价补肾活血中药治疗高催乳素血症的临床疗效，为补肾活血中药治疗高催乳素血症提供循证医学依据。通过计算机全面检索PubMed、EMbase、Cochrane Library、CNKI、万方、维普、CBM中补肾活血中药治疗高催乳素血症的随机对照试验并进行Meta分析。检索时间自建库至2018年9月28日。13项临床研究共纳入816例符合纳入标准的高催乳素血症患者。Meta分析结果显示，与西药相比，补肾活血中药在降低催乳素水平、治疗不孕方面疗效相当，在改善中医证候、降低疾病复发率及减少不良反应方面具有明显优势。
