Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Department of Obstetrics and Gynecology, Shandong Provincial Hospital Affiliated to Shandong University, Shandong, China.
J Clin Hypertens (Greenwich). 2019 May;21(5):618-623. doi: 10.1111/jch.13541. Epub 2019 Apr 16.
A cross-sectional study was conducted to the reported factors and assesses possible protective factors for pregnancy-induced hypertension (PIH) in China. The data of pregnant women who delivered between October 2016 and September 2017 were collected from a birth registry. The primary outcome was the occurrence of PIH. Secondary outcomes were delivery before 34 gestational weeks and other adverse obstetric outcomes of PIH. Among the 99 535 women enrolled, 5731 women (5.8%) developed PIH. BMI had a positive correlation with the primary and two secondary outcomes (adjusted OR = 2.05, 2.56, 1.87, respectively, for overweight; adjusted OR = 4.44, 3.90, and 2.63, respectively, for obesity). Otherwise, calcium supplementation during pregnancy was a potential protective factor for those outcomes (adjusted OR = 0.87, 0.14, and 0.44, respectively). These results provide a basis for PIH prevention strategy in the Chinese public health sector. Calcium supplementation and lowering the BMI might have the potential benefit on reducing the prevalence of PIH in selected women.
一项横断面研究报告了中国妊娠高血压（PIH）的相关因素，并评估了可能的保护因素。该研究的数据来自于 2016 年 10 月至 2017 年 9 月间的出生登记处。主要结局是 PIH 的发生。次要结局是 34 孕周前分娩和 PIH 的其他不良产科结局。在纳入的 99535 名妇女中，有 5731 名（5.8%）发生了 PIH。BMI 与主要和两个次要结局呈正相关（超重的调整 OR 分别为 2.05、2.56 和 1.87；肥胖的调整 OR 分别为 4.44、3.90 和 2.63）。相反，怀孕期间补充钙是这些结局的潜在保护因素（调整 OR 分别为 0.87、0.14 和 0.44）。这些结果为中国公共卫生部门的 PIH 预防策略提供了依据。钙补充和降低 BMI 可能对降低特定妇女的 PIH 患病率有潜在益处。
