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用溶解的同基因肿瘤细胞质膜二次诱导细胞毒性T淋巴细胞。

Secondary induction of cytotoxic T lymphocytes with solubilized syngeneic tumor cell plasma membranes.

作者信息

Alaba O, Law L W

出版信息

J Exp Med. 1978 Nov 1;148(5):1435-9. doi: 10.1084/jem.148.5.1435.

Abstract

Secondary induction of in vitro cytotoxic T lymphocytes in a syngeneic system has been achieved with plasma membrane, both in the particulate and solubilized forms. Both the induction and the lytic phases were shown to be immunologically specific. The effector cells generated were completely susceptible to treatment with anti-theta antibody and complement, suggesting that they are T lymphocytes.

摘要

在同基因系统中,已通过颗粒形式和可溶形式的质膜实现了体外细胞毒性T淋巴细胞的二次诱导。诱导阶段和裂解阶段均显示出免疫特异性。所产生的效应细胞完全易受抗θ抗体和补体处理的影响,表明它们是T淋巴细胞。

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