Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USA.
Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON K1H 8L1, Canada.
Nutrients. 2019 Apr 15;11(4):848. doi: 10.3390/nu11040848.
The purpose of this review is to summarize the scientific contributions of the International Study of Childhood Obesity, Lifestyle and the Environment (ISCOLE) in extending our understanding about obesity in children from around the world. ISCOLE was a multi-national study of 9 to 11 year-old children from sites in 12 countries from all inhabited continents. The primary purpose was to investigate relationships between lifestyle behaviors and obesity, and the influence of higher-order characteristics such as behavioral settings, and physical, social and policy environments. ISCOLE has made several advances in scientific methodology related to the assessment of physical activity, dietary behavior, sleep and the neighborhood and school environments. Furthermore, ISCOLE has provided important evidence on (1) epidemiological transitions in obesity and related behaviors, (2) correlates of obesity and lifestyle behaviors at the individual, neighborhood and school levels, and (3) 24-h movement behaviors in relation to novel analytical techniques. A key feature of ISCOLE was the development of a platform for international training, data entry, and data quality for multi-country studies. Finally, ISCOLE represents a transparent model for future public-private research partnerships across low, middle and high-income countries.
本次综述旨在总结国际儿童肥胖症、生活方式和环境研究（ISCOLE）的科学贡献，增进我们对来自世界各地儿童肥胖症的认识。ISCOLE 是一项多国家研究，涉及来自 12 个国家 12 个地区的 9 至 11 岁儿童。主要目的是调查生活方式行为与肥胖之间的关系，以及行为环境、身体、社会和政策环境等更高阶特征的影响。ISCOLE 在评估身体活动、饮食行为、睡眠以及邻里和学校环境方面的科学方法上取得了多项进展。此外，ISCOLE 还提供了重要证据：（1）肥胖症及相关行为的流行病学转变；（2）个体、邻里和学校层面肥胖症和生活方式行为的相关性；（3）24 小时运动行为与新分析技术的关系。ISCOLE 的一个重要特点是为多国研究开发了一个国际培训、数据输入和数据质量的平台。最后，ISCOLE 为中低收入国家和高收入国家之间的未来公私研究伙伴关系提供了一个透明的模式。
