Research Institute, Suntory Global Innovation Center Ltd., 8-1-1 Seikadai, Seika, Kyoto, 619-0284, Japan.
Lipids Health Dis. 2019 Apr 16;18(1):101. doi: 10.1186/s12944-019-1039-y.
Long-chain polyunsaturated fatty acids (LCPUFAs) have important roles in physiological homeostasis. Numerous studies have provided extensive information about the roles of n-3 LCPUFA, such as docosahexaenoic acid and eicosapentaenoic acid. Arachidonic acid (ARA) is one of the major n-6 LCPUFAs and its biological aspects have been well studied. However, nutritional information for ARA is limited, especially in adult humans. This review presents a framework of dietary ARA intake and the effects of ARA supplementation on LCPUFA metabolism in adult humans, and the nutritional significance of ARA and LCPUFA is discussed.
长链多不饱和脂肪酸(LCPUFAs)在生理稳态中具有重要作用。许多研究提供了大量关于 n-3 LCPUFA(如二十二碳六烯酸和二十碳五烯酸)作用的信息。花生四烯酸(ARA)是主要的 n-6 LCPUFA 之一,其生物学方面已经得到了充分的研究。然而,ARA 的营养信息有限,特别是在成年人群中。本综述介绍了成人摄入 ARA 的饮食框架以及 ARA 补充对 LCPUFA 代谢的影响,并讨论了 ARA 和 LCPUFA 的营养意义。