• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

成年人摄入含花生四烯酸的脂质:膳食调查和临床试验。

Intake of arachidonic acid-containing lipids in adult humans: dietary surveys and clinical trials.

机构信息

Research Institute, Suntory Global Innovation Center Ltd., 8-1-1 Seikadai, Seika, Kyoto, 619-0284, Japan.

出版信息

Lipids Health Dis. 2019 Apr 16;18(1):101. doi: 10.1186/s12944-019-1039-y.

DOI:10.1186/s12944-019-1039-y
PMID:30992005
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6469145/
Abstract

Long-chain polyunsaturated fatty acids (LCPUFAs) have important roles in physiological homeostasis. Numerous studies have provided extensive information about the roles of n-3 LCPUFA, such as docosahexaenoic acid and eicosapentaenoic acid. Arachidonic acid (ARA) is one of the major n-6 LCPUFAs and its biological aspects have been well studied. However, nutritional information for ARA is limited, especially in adult humans. This review presents a framework of dietary ARA intake and the effects of ARA supplementation on LCPUFA metabolism in adult humans, and the nutritional significance of ARA and LCPUFA is discussed.

摘要

长链多不饱和脂肪酸(LCPUFAs)在生理稳态中具有重要作用。许多研究提供了大量关于 n-3 LCPUFA(如二十二碳六烯酸和二十碳五烯酸)作用的信息。花生四烯酸(ARA)是主要的 n-6 LCPUFA 之一,其生物学方面已经得到了充分的研究。然而,ARA 的营养信息有限,特别是在成年人群中。本综述介绍了成人摄入 ARA 的饮食框架以及 ARA 补充对 LCPUFA 代谢的影响,并讨论了 ARA 和 LCPUFA 的营养意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9aa/6469145/da19126847d5/12944_2019_1039_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9aa/6469145/60e48e63f033/12944_2019_1039_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9aa/6469145/da19126847d5/12944_2019_1039_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9aa/6469145/60e48e63f033/12944_2019_1039_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9aa/6469145/da19126847d5/12944_2019_1039_Fig2_HTML.jpg

相似文献

1
Intake of arachidonic acid-containing lipids in adult humans: dietary surveys and clinical trials.成年人摄入含花生四烯酸的脂质:膳食调查和临床试验。
Lipids Health Dis. 2019 Apr 16;18(1):101. doi: 10.1186/s12944-019-1039-y.
2
Relationship between Long Chain n-3 Polyunsaturated Fatty Acids and Autism Spectrum Disorder: Systematic Review and Meta-Analysis of Case-Control and Randomised Controlled Trials.长链n-3多不饱和脂肪酸与自闭症谱系障碍之间的关系:病例对照研究和随机对照试验的系统评价与荟萃分析
Nutrients. 2017 Feb 19;9(2):155. doi: 10.3390/nu9020155.
3
Lower n-3 long-chain polyunsaturated fatty acid values in patients with phenylketonuria: a systematic review and meta-analysis.苯丙酮尿症患者 n-3 长链多不饱和脂肪酸值降低:系统评价和荟萃分析。
Nutr Res. 2013 Jul;33(7):513-20. doi: 10.1016/j.nutres.2013.05.003. Epub 2013 Jun 10.
4
Age-related changes of dietary intake and blood eicosapentaenoic acid, docosahexaenoic acid, and arachidonic acid levels in Japanese men and women.年龄相关的日本男女饮食摄入和血液二十碳五烯酸、二十二碳六烯酸和花生四烯酸水平的变化。
Prostaglandins Leukot Essent Fatty Acids. 2011 May-Jun;84(5-6):131-7. doi: 10.1016/j.plefa.2011.01.001. Epub 2011 Mar 21.
5
Long-chain Polyunsaturated Fatty Acid Supplementation Improves Mood in Elderly Japanese Men.补充长链多不饱和脂肪酸可改善日本老年男性的情绪。
J Oleo Sci. 2017 Jul 1;66(7):713-721. doi: 10.5650/jos.ess17035. Epub 2017 Jun 13.
6
Low Doses of Long-chain Polyunsaturated Fatty Acids Affect Cognitive Function in Elderly Japanese Men: A Randomized Controlled Trial.低剂量长链多不饱和脂肪酸对日本老年男性认知功能的影响:一项随机对照试验。
J Oleo Sci. 2015;64(6):633-44. doi: 10.5650/jos.ess15009. Epub 2015 Apr 20.
7
Randomized Controlled Trial of Early Docosahexaenoic Acid and Arachidonic Acid Enteral Supplementation in Very Low Birth Weight Infants.随机对照试验:早期二十二碳六烯酸和花生四烯酸肠内补充对极低出生体重儿的影响。
J Pediatr. 2021 May;232:23-30.e1. doi: 10.1016/j.jpeds.2020.12.037. Epub 2021 Feb 20.
8
Higher serum EPA or DHA, and lower ARA compositions with age independent fatty acid intake in Japanese aged 40 to 79.在40至79岁的日本人中,血清二十碳五烯酸(EPA)或二十二碳六烯酸(DHA)水平较高,且随着年龄增长,花生四烯酸(ARA)含量较低,脂肪酸摄入量与年龄无关。
Lipids. 2013 Jul;48(7):719-27. doi: 10.1007/s11745-013-3763-9. Epub 2013 Feb 7.
9
Dietary intake and plasma metabolomic analysis of polyunsaturated fatty acids in bipolar subjects reveal dysregulation of linoleic acid metabolism.双相情感障碍患者多不饱和脂肪酸的饮食摄入与血浆代谢组学分析揭示了亚油酸代谢的失调。
J Psychiatr Res. 2014 Oct;57:58-64. doi: 10.1016/j.jpsychires.2014.06.001. Epub 2014 Jun 12.
10
Docosahexaenoic acid in red blood cells of term infants receiving two levels of long-chain polyunsaturated fatty acids.足月婴儿红细胞中二十二碳六烯酸与两种水平的长链多不饱和脂肪酸的关系
J Pediatr Gastroenterol Nutr. 2006 Mar;42(3):287-92. doi: 10.1097/01.mpg.0000189366.91792.64.

引用本文的文献

1
Investigating Multi-Omic Signatures of Ethnicity and Dysglycaemia in Asian Chinese and European Caucasian Adults: Cross-Sectional Analysis of the TOFI_Asia Study at 4-Year Follow-Up.亚洲华裔和欧洲白种成年人中种族与血糖异常的多组学特征研究:TOFI_Asia研究4年随访的横断面分析
Metabolites. 2025 Aug 1;15(8):522. doi: 10.3390/metabo15080522.
2
Arachidonic acid as a potentially critical nutrient for vegetarians and vegans - position paper of the Research Institute for Plant-based Nutrition (IFPE).花生四烯酸作为素食者和纯素食者潜在的关键营养素——植物性营养研究所(IFPE)立场文件
Lipids Health Dis. 2025 Jul 19;24(1):244. doi: 10.1186/s12944-025-02645-z.
3

本文引用的文献

1
Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease.ω-3脂肪酸用于心血管疾病的一级和二级预防。
Cochrane Database Syst Rev. 2018 Nov 30;11(11):CD003177. doi: 10.1002/14651858.CD003177.pub4.
2
Polyunsaturated fatty acids, inflammation, and metabolic syndrome in South Asian Americans in Maryland.马里兰州南亚裔美国人中的多不饱和脂肪酸、炎症与代谢综合征
Food Sci Nutr. 2018 Jul 16;6(6):1575-1581. doi: 10.1002/fsn3.698. eCollection 2018 Sep.
3
Arachidonic acid production by the oleaginous fungus 1S-4: A review.
Polyunsaturated fatty acids in lipid membranes regulate human neuronal function and amyloid-β production.
脂质膜中的多不饱和脂肪酸调节人类神经元功能和β-淀粉样蛋白的产生。
iScience. 2025 May 12;28(6):112557. doi: 10.1016/j.isci.2025.112557. eCollection 2025 Jun 20.
4
Biochemical and molecular characterization of fungal isolates from California annual grassland soil.来自加利福尼亚一年生草地土壤的真菌分离株的生化与分子特征分析
Biotechnol Biofuels Bioprod. 2025 May 31;18(1):56. doi: 10.1186/s13068-025-02651-4.
5
Positive Psychiatry and Healthy Lifestyle Interventions Augmenting Psychotherapy for Mood Disorders.积极精神病学与健康生活方式干预增强情绪障碍心理治疗效果
Innov Clin Neurosci. 2025 Mar 1;22(1-3):20-27. eCollection 2025 Jan-Mar.
6
Comparative analysis of fatty acid profiles across omnivorous, flexitarians, vegetarians, and vegans: insights from the NuEva study.杂食者、弹性素食者、素食者和纯素食者脂肪酸谱的比较分析:来自NuEva研究的见解
Lipids Health Dis. 2025 Apr 9;24(1):133. doi: 10.1186/s12944-025-02517-6.
7
Exploring the connection between erythrocyte membrane fatty acid composition and oxidative stress in patients undergoing the Crohn's disease Therapeutic Diet Intervention (CD-TDI).探索接受克罗恩病治疗性饮食干预(CD-TDI)患者的红细胞膜脂肪酸组成与氧化应激之间的联系。
Therap Adv Gastroenterol. 2025 Feb 16;18:17562848251314827. doi: 10.1177/17562848251314827. eCollection 2025.
8
Association Between Circulating Fatty Acids and Blood Pressure: A Review.循环脂肪酸与血压之间的关联:综述
Curr Nutr Rep. 2025 Jan 8;14(1):15. doi: 10.1007/s13668-024-00602-3.
9
A Survey of Fatty Acid Content of the Male Reproductive System in Mice Supplemented With Arachidonic Acid.补充花生四烯酸的小鼠雄性生殖系统脂肪酸含量的调查
J Lipids. 2024 Dec 19;2024:3351340. doi: 10.1155/jl/3351340. eCollection 2024.
10
Trans, Trans-Farnesol Enhances the Anti-Bacterial and Anti-Biofilm Effect of Arachidonic Acid on the Cariogenic Bacteria and .反式,反式法呢醇增强花生四烯酸对致龋菌的抗菌和抗生物膜作用。
Int J Mol Sci. 2024 Nov 1;25(21):11770. doi: 10.3390/ijms252111770.
产油真菌1S-4合成花生四烯酸的研究综述
J Adv Res. 2018 Feb 8;11:15-22. doi: 10.1016/j.jare.2018.02.003. eCollection 2018 May.
4
2-Arachidonoylglycerol: A signaling lipid with manifold actions in the brain.2-花生四烯酸甘油酯:一种在大脑中具有多种作用的信号脂质。
Prog Lipid Res. 2018 Jul;71:1-17. doi: 10.1016/j.plipres.2018.05.002. Epub 2018 May 8.
5
DHA and ARA addition to infant formula: Current status and future research directions.婴儿配方奶粉中添加 DHA 和 ARA:现状和未来研究方向。
Prostaglandins Leukot Essent Fatty Acids. 2018 Jan;128:26-40. doi: 10.1016/j.plefa.2017.09.005. Epub 2017 Sep 15.
6
Long-chain omega-3 polyunsaturated fatty acid dietary intake is positively associated with bone mineral density in normal and osteopenic Spanish women.在正常及骨质减少的西班牙女性中,长链ω-3多不饱和脂肪酸的膳食摄入量与骨矿物质密度呈正相关。
PLoS One. 2018 Jan 5;13(1):e0190539. doi: 10.1371/journal.pone.0190539. eCollection 2018.
7
Long-chain Polyunsaturated Fatty Acid Supplementation Improves Mood in Elderly Japanese Men.补充长链多不饱和脂肪酸可改善日本老年男性的情绪。
J Oleo Sci. 2017 Jul 1;66(7):713-721. doi: 10.5650/jos.ess17035. Epub 2017 Jun 13.
8
Effects of docosahexaenoic acid supplementation on PUFA levels in red blood cells and plasma.补充二十二碳六烯酸对红细胞和血浆中多不饱和脂肪酸水平的影响。
Prostaglandins Leukot Essent Fatty Acids. 2016 Dec;115:12-23. doi: 10.1016/j.plefa.2016.10.005. Epub 2016 Oct 12.
9
Periodontal condition in relation to intake of omega-3 and omega-6 polyunsaturated fatty acids.与ω-3和ω-6多不饱和脂肪酸摄入相关的牙周状况
J Clin Periodontol. 2016 Nov;43(11):901-908. doi: 10.1111/jcpe.12599. Epub 2016 Sep 27.
10
Docosahexaenoic Acid and Arachidonic Acid Nutrition in Early Development.早期发育中的二十二碳六烯酸和花生四烯酸营养
Adv Pediatr. 2016 Aug;63(1):453-71. doi: 10.1016/j.yapd.2016.04.011. Epub 2016 Jun 3.