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实施 2013-2016 年南非马拉维、坦桑尼亚联合共和国农村地区母婴传播艾滋病毒预防政策。

Implementing prevention policies for mother-to-child transmission of HIV in rural Malawi, South Africa and United Republic of Tanzania, 2013-2016.

机构信息

Department of Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England.

Malawi Epidemiology and Intervention Research Unit, Lilongwe, Malawi.

出版信息

Bull World Health Organ. 2019 Mar 1;97(3):200-212. doi: 10.2471/BLT.18.217471. Epub 2019 Jan 28.

Abstract

OBJECTIVE

To assess adoption of World Health Organization (WHO) guidance into national policies for prevention of mother-to-child transmission (PMTCT) of human immunodeficiency virus (HIV) and to monitor implementation of guidelines at facility level in rural Malawi, South Africa and the United Republic of Tanzania.

METHODS

We summarized national PMTCT policies and WHO guidance for 15 indicators across the cascades of maternal and infant care over 2013-2016. Two survey rounds were conducted (2013-2015 and 2015-2016) in 46 health facilities serving five health and demographic surveillance system populations. We administered structured questionnaires to facility managers to describe service delivery. We report the proportions of facilities implementing each indicator and the frequency and durations of stock-outs of supplies, by site and survey round.

FINDINGS

In all countries, national policies influencing the maternal and infant PMTCT cascade of care aligned with WHO guidelines by 2016; most inter-country policy variations concerned linkage to routine HIV care. The proportion of facilities delivering post-test counselling, same-day antiretroviral therapy (ART) initiation, antenatal care and ART provision in the same building, and Option B+ increased or remained at 100% in all sites. Progress in implementing policies on infant diagnosis and treatment varied across sites. Stock-outs of HIV test kits or antiretroviral drugs in the past year declined overall, but were reported by at least one facility per site in both rounds.

CONCLUSION

Progress has been made in implementing PMTCT policy in these settings. However, persistent gaps across the infant cascade of care and supply-chain challenges, risk undermining infant HIV elimination goals.

摘要

目的

评估世界卫生组织(WHO)指导方针在各国预防母婴传播(PMTCT)艾滋病毒(HIV)政策中的采用情况,并监测南非、马拉维共和国和坦桑尼亚联合共和国农村地区设施层面指南的执行情况。

方法

我们总结了 2013-2016 年间母婴护理级联的 15 项指标的国家 PMTCT 政策和 WHO 指南。在为五个卫生和人口监测系统人群服务的 46 个卫生设施中进行了两轮调查(2013-2015 年和 2015-2016 年)。我们向设施管理人员发放了结构化问卷,以描述服务提供情况。我们按地点和调查轮次报告实施每个指标的设施比例以及供应品缺货的频率和持续时间。

发现

到 2016 年,所有国家影响母婴 PMTCT 级联护理的国家政策都与 WHO 指南一致;大多数国家间政策差异涉及与常规 HIV 护理的联系。在所有地点,提供检测后咨询、同日开始抗逆转录病毒治疗(ART)、在同一栋楼内进行产前护理和提供 ART,以及实施 B+方案的设施比例均增加或保持在 100%。在实施婴儿诊断和治疗政策方面,各地进展情况各不相同。在过去一年中,艾滋病毒检测试剂盒或抗逆转录病毒药物的缺货情况总体上有所减少,但在两轮调查中,每个地点都至少有一家设施报告存在缺货情况。

结论

在这些环境中,PMTCT 政策的实施已经取得进展。然而,婴儿级联护理和供应链挑战方面仍然存在差距,这可能会破坏婴儿艾滋病毒消除目标。

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