Suppr超能文献

老年髋部骨折患者合并症与治疗决策的关系。

Relationship between comorbidities and treatment decision-making in elderly hip fracture patients.

机构信息

Department of Geriatrics, West China Hospital, Sichuan University, NO. 37 GuoXue Road, Chengdu, 610041, Sichuan, China.

Department of Geriatrics, Sichuan Provincial People's Hospital, Chengdu, 610072, China.

出版信息

Aging Clin Exp Res. 2019 Dec;31(12):1735-1741. doi: 10.1007/s40520-019-01134-5. Epub 2019 Apr 16.

Abstract

BACKGROUND

Elderly patients are at a higher risk for hip fracture. Moreover, hospitalized elderly patients with hip fracture are vulnerable to adverse outcomes including higher mortality rate and long-term disability. Treatment decision-making with respect to surgical procedure and perioperative management of these patients is typically challenging owing to the presence of multiple comorbid conditions.

AIMS

The purpose of this study was to investigate the relationship between comorbidities in elderly patients with hip fracture and the treatment decision-making.

METHODS

884 geriatric patients (age ≥ 60 years) with hip fracture were included. Comorbidities related to age were measured using the Charlson Co-morbidity Index (CCI) and age-adjusted CCI. The CCI of each geriatric hip fracture patient was calculated based on data retrieved from the medical records. The relationship of CCI and age-adjusted CCI with surgical procedure, time-to-surgery, length of hospital stay, and perioperative management (transfusion, anti-coagulation, and analgesia) was assessed.

RESULTS

Mean age of patients was 78.01 ± 8.62 years. The mean CCI was 0.79 ± 0.036; the mean age-adjusted CCI was 4.15 ± 0.047. The CCI was significantly associated with time-to-surgery (P = 0.004), surgical treatment (P < 0.001), and transfusion (P = 0.023). The age-adjusted CCI was significantly associated with surgical treatment (P < 0.001), analgesia (P = 0.003) and transfusion (P < 0.001). The length of hospital stay was associated with both CCI (P = 0.041), age-adjusted CCI (P = 0.002), and hypertension (P = 0.012). Hospital expenses showed a significant association with CCI (P = 0.000), age-adjusted CCI (P = 0.029), osteoprosis (P = 0.007), and hypertension (P = 0.001).

CONCLUSION

In this study, comorbidities were positively associated with surgical procedure and perioperative management of elderly patients with hip fracture.

摘要

背景

老年患者髋部骨折风险更高。此外,住院老年髋部骨折患者易发生不良结局,包括死亡率较高和长期残疾。由于存在多种合并症,这些患者的手术程序和围手术期管理的治疗决策通常具有挑战性。

目的

本研究旨在探讨老年髋部骨折患者的合并症与治疗决策之间的关系。

方法

纳入 884 例老年髋部骨折患者(年龄≥60 岁)。使用 Charlson 合并症指数(CCI)和年龄调整后的 CCI 来衡量与年龄相关的合并症。根据从病历中检索到的数据,计算每位老年髋部骨折患者的 CCI。评估 CCI 和年龄调整后的 CCI 与手术程序、手术时间、住院时间和围手术期管理(输血、抗凝和镇痛)的关系。

结果

患者平均年龄为 78.01±8.62 岁。平均 CCI 为 0.79±0.036;平均年龄调整后的 CCI 为 4.15±0.047。CCI 与手术时间(P=0.004)、手术治疗(P<0.001)和输血(P=0.023)显著相关。年龄调整后的 CCI 与手术治疗(P<0.001)、镇痛(P=0.003)和输血(P<0.001)显著相关。住院时间与 CCI(P=0.041)、年龄调整后的 CCI(P=0.002)和高血压(P=0.012)相关。住院费用与 CCI(P=0.000)、年龄调整后的 CCI(P=0.029)、骨质疏松症(P=0.007)和高血压(P=0.001)显著相关。

结论

在这项研究中,合并症与老年髋部骨折患者的手术程序和围手术期管理呈正相关。

相似文献

1
Relationship between comorbidities and treatment decision-making in elderly hip fracture patients.
Aging Clin Exp Res. 2019 Dec;31(12):1735-1741. doi: 10.1007/s40520-019-01134-5. Epub 2019 Apr 16.
4
The effect of the comorbidity burden on vitamin D levels in geriatric hip fracture.
BMC Musculoskelet Disord. 2020 Aug 8;21(1):524. doi: 10.1186/s12891-020-03554-1.
5
Relationship between the Charlson Comorbidity Index and cost of treating hip fractures: implications for bundled payment.
J Orthop Traumatol. 2015 Sep;16(3):209-13. doi: 10.1007/s10195-015-0337-z. Epub 2015 Feb 20.
7
Epidemiological and clinical study of hip fracture in hospitalized elderly patients in Shanghai, China.
Arch Osteoporos. 2019 Mar 12;14(1):37. doi: 10.1007/s11657-019-0580-7.
9
Comorbidity as the dominant predictor of mortality after hip fracture surgeries.
Osteoporos Int. 2019 Dec;30(12):2477-2483. doi: 10.1007/s00198-019-05139-8. Epub 2019 Aug 26.

引用本文的文献

2
Anemia as a mediator: bridging the frailty index and hip fractures in older Chinese populations.
Front Public Health. 2025 Apr 23;13:1558074. doi: 10.3389/fpubh.2025.1558074. eCollection 2025.
3
Risk factors associated with mortality in elderly patients receiving hemiarthroplasty for femoral neck fractures.
BMC Musculoskelet Disord. 2025 Apr 16;26(1):373. doi: 10.1186/s12891-025-08620-0.
4
A real-world analysis of 1,823 hospitalized osteoporotic fractures in Northeast China.
Front Endocrinol (Lausanne). 2025 Jan 7;15:1520229. doi: 10.3389/fendo.2024.1520229. eCollection 2024.
5
Clinical, laboratory, and hospital factors associated with preoperative complications in Peruvian older adults with hip fracture.
PLoS One. 2024 Nov 4;19(11):e0313089. doi: 10.1371/journal.pone.0313089. eCollection 2024.
7
Risk Factors of Serious Adverse Events for Geriatric Hip Fractures: Is it the Frailty or the Timing?
Geriatr Orthop Surg Rehabil. 2024 Apr 25;15:21514593241250165. doi: 10.1177/21514593241250165. eCollection 2024.
8
Enhanced Recovery After Surgery (ERAS) Protocol in Geriatric Hip Fractures: An Observational Study.
Cureus. 2023 Jul 18;15(7):e42073. doi: 10.7759/cureus.42073. eCollection 2023 Jul.

本文引用的文献

1
Geriatric Patients with Hip Fracture: Frailty and Other Risk Factors Affecting the Outcome.
Anesth Essays Res. 2018 Apr-Jun;12(2):546-551. doi: 10.4103/aer.AER_61_18.
2
Prognostic factors and predictive model for in-hospital mortality following hip fractures in the elderly.
Chin J Traumatol. 2018 Jun;21(3):163-169. doi: 10.1016/j.cjtee.2017.10.006. Epub 2018 Apr 25.
3
Prognostic factors of functional outcome after hip fracture surgery: a systematic review.
Age Ageing. 2018 Sep 1;47(5):661-670. doi: 10.1093/ageing/afy057.
4
Can we predict postoperative complications in elderly Chinese patients with hip fractures using the surgical risk calculator?
Clin Interv Aging. 2017 Sep 22;12:1515-1520. doi: 10.2147/CIA.S142748. eCollection 2017.
5
Early surgery for Hong Kong Chinese elderly patients with hip fracture reduces short-term and long-term mortality.
Hong Kong Med J. 2017 Aug;23(4):374-80. doi: 10.12809/hkmj165005. Epub 2017 Jun 28.
6
Risk factors for in-hospital mortality following hip fracture.
Rev Esp Cir Ortop Traumatol. 2017 Jul-Aug;61(4):209-215. doi: 10.1016/j.recot.2017.03.003. Epub 2017 Apr 24.
7
Risk-factors for surgical delay following hip fracture.
Rev Esp Cir Ortop Traumatol. 2017 May-Jun;61(3):162-169. doi: 10.1016/j.recot.2017.02.001. Epub 2017 Mar 31.
8
Dementia and delirium, the outcomes in elderly hip fracture patients.
Clin Interv Aging. 2017 Mar 10;12:421-430. doi: 10.2147/CIA.S115945. eCollection 2017.
9
Mortality after proximal hip fracture in the Singapore population.
Hip Int. 2005 Jul-Sep;15(3):166-170. doi: 10.1177/112070000501500307.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验