Department of Geriatrics, West China Hospital, Sichuan University, NO. 37 GuoXue Road, Chengdu, 610041, Sichuan, China.
Department of Geriatrics, Sichuan Provincial People's Hospital, Chengdu, 610072, China.
Aging Clin Exp Res. 2019 Dec;31(12):1735-1741. doi: 10.1007/s40520-019-01134-5. Epub 2019 Apr 16.
Elderly patients are at a higher risk for hip fracture. Moreover, hospitalized elderly patients with hip fracture are vulnerable to adverse outcomes including higher mortality rate and long-term disability. Treatment decision-making with respect to surgical procedure and perioperative management of these patients is typically challenging owing to the presence of multiple comorbid conditions.
The purpose of this study was to investigate the relationship between comorbidities in elderly patients with hip fracture and the treatment decision-making.
884 geriatric patients (age ≥ 60 years) with hip fracture were included. Comorbidities related to age were measured using the Charlson Co-morbidity Index (CCI) and age-adjusted CCI. The CCI of each geriatric hip fracture patient was calculated based on data retrieved from the medical records. The relationship of CCI and age-adjusted CCI with surgical procedure, time-to-surgery, length of hospital stay, and perioperative management (transfusion, anti-coagulation, and analgesia) was assessed.
Mean age of patients was 78.01 ± 8.62 years. The mean CCI was 0.79 ± 0.036; the mean age-adjusted CCI was 4.15 ± 0.047. The CCI was significantly associated with time-to-surgery (P = 0.004), surgical treatment (P < 0.001), and transfusion (P = 0.023). The age-adjusted CCI was significantly associated with surgical treatment (P < 0.001), analgesia (P = 0.003) and transfusion (P < 0.001). The length of hospital stay was associated with both CCI (P = 0.041), age-adjusted CCI (P = 0.002), and hypertension (P = 0.012). Hospital expenses showed a significant association with CCI (P = 0.000), age-adjusted CCI (P = 0.029), osteoprosis (P = 0.007), and hypertension (P = 0.001).
In this study, comorbidities were positively associated with surgical procedure and perioperative management of elderly patients with hip fracture.
老年患者髋部骨折风险更高。此外,住院老年髋部骨折患者易发生不良结局,包括死亡率较高和长期残疾。由于存在多种合并症,这些患者的手术程序和围手术期管理的治疗决策通常具有挑战性。
本研究旨在探讨老年髋部骨折患者的合并症与治疗决策之间的关系。
纳入 884 例老年髋部骨折患者(年龄≥60 岁)。使用 Charlson 合并症指数(CCI)和年龄调整后的 CCI 来衡量与年龄相关的合并症。根据从病历中检索到的数据,计算每位老年髋部骨折患者的 CCI。评估 CCI 和年龄调整后的 CCI 与手术程序、手术时间、住院时间和围手术期管理(输血、抗凝和镇痛)的关系。
患者平均年龄为 78.01±8.62 岁。平均 CCI 为 0.79±0.036;平均年龄调整后的 CCI 为 4.15±0.047。CCI 与手术时间(P=0.004)、手术治疗(P<0.001)和输血(P=0.023)显著相关。年龄调整后的 CCI 与手术治疗(P<0.001)、镇痛(P=0.003)和输血(P<0.001)显著相关。住院时间与 CCI(P=0.041)、年龄调整后的 CCI(P=0.002)和高血压(P=0.012)相关。住院费用与 CCI(P=0.000)、年龄调整后的 CCI(P=0.029)、骨质疏松症(P=0.007)和高血压(P=0.001)显著相关。
在这项研究中,合并症与老年髋部骨折患者的手术程序和围手术期管理呈正相关。