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口腔扁平苔藓的临床症状与口腔健康相关生活质量的关系。

The relationship between clinical symptoms of oral lichen planus and quality of life related to oral health.

机构信息

Kerman Social Determinants On Oral Health Research Center, Kerman University of Medical Sciences, Kerman, Iran.

Department of Oral Medicine, School of Dentistry, Kerman University of Medical Sciences, Kerman, Iran.

出版信息

BMC Oral Health. 2024 May 13;24(1):556. doi: 10.1186/s12903-024-04326-2.

Abstract

INTRODUCTION

Oral Lichen Planus (OLP) is a chronic and relatively common mucocutaneous disease that often affects the oral mucosa. Although, OLP is generally not life-threatening, its consequences can significantly impact the quality of life in physical, psychological, and social aspects. Therefore, the aim of this research is to investigate the relationship between clinical symptoms of OLP and oral health-related quality of life in patients using the OHIP-14 (Oral Health Impact Profile-14) questionnaire.

MATERIALS AND METHODS

This descriptive-analytical study has a cross-sectional design, with case-control comparison. In this study, 56 individuals were examined as cases, and 68 individuals were included as controls. After recording demographic characteristics and clinical features by reviewing patients' records, the OHIP-14 questionnaire including clinical severity of lesions assessed using the Thongprasom scoring system, and pain assessed by the Visual Analog Scale (VAS) were completed. The ADD (Additive) and SC (Simple Count) methods were used for scoring, and data analysis was performed using the T-test, Mann-Whitney U test, Chi-Square, Spearman's Correlation Coefficient, and SPSS 24.

RESULTS

Nearly all patients (50 individuals, 89.3%) reported having pain, although the average pain intensity was mostly mild. This disease has affected the quality of life in 82% of the patients (46 individuals). The patient group, in comparison to the control group, significantly expressed a lower quality of life in terms of functional limitations and physical disability. There was a statistically significant positive correlation between clinical symptoms of OLP, gender, location (palate), and clinical presentation type (erosive, reticular, and bullous) of OLP lesions with OHIP-14 scores, although the number or bilaterality of lesions and patient age did not have any significant correlation with pain or OHIP scores.

CONCLUSION

It appears that certain aspects of oral health-related quality of life decrease in patients with OLP, and that of the OLP patient group is significantly lower in terms of functional limitations and physical disability compared to the control group. Additionally, there was a significant correlation between clinical symptoms of OLP and pain as well as OHIP scores.

摘要

简介

口腔扁平苔藓(OLP)是一种常见的慢性黏膜疾病,常发生于口腔黏膜。虽然 OLP 一般不会危及生命,但它会对患者的身体、心理和社会方面的生活质量产生重大影响。因此,本研究旨在通过使用 OHIP-14(口腔健康影响概况-14)问卷来调查 OLP 患者的临床症状与口腔健康相关生活质量之间的关系。

材料与方法

本研究为描述性分析研究,采用病例对照比较设计。本研究共纳入 56 例病例和 68 例对照。通过查阅患者病历记录,记录患者的人口统计学特征和临床特征,使用 Thongprasom 评分系统评估病变的临床严重程度,并使用视觉模拟量表(VAS)评估疼痛,完成 OHIP-14 问卷。采用 ADD(加总)和 SC(简单计数)评分法进行评分,采用 T 检验、Mann-Whitney U 检验、卡方检验、Spearman 相关系数和 SPSS 24 进行数据分析。

结果

几乎所有患者(50 例,89.3%)均报告有疼痛,但平均疼痛强度大多为轻度。该疾病影响了 82%的患者(46 例)的生活质量。与对照组相比,患者组在功能受限和身体残疾方面明显表示生活质量较低。OLP 患者的临床症状、性别、病变位置(上颚)和临床表现类型(糜烂型、网状型和大疱型)与 OHIP-14 评分之间存在显著的正相关关系,但病变数量或双侧性以及患者年龄与疼痛或 OHIP 评分无显著相关性。

结论

OLP 患者的某些口腔健康相关生活质量方面似乎会下降,与对照组相比,OLP 患者组在功能受限和身体残疾方面的生活质量显著较低。此外,OLP 的临床症状与疼痛和 OHIP 评分之间存在显著相关性。

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