大鼠在哺乳期及幼崽被移走后的即刻阶段膳食脂质保存的证据。口服[1-14C]三油酸甘油酯的氧化减少。
Evidence for conservation of dietary lipid in the rat during lactation and the immediate period after removal of the litter. Decreased oxidation of oral [1-14C]triolein.
作者信息
Oller do Nascimento C M, Williamson D H
出版信息
Biochem J. 1986 Oct 1;239(1):233-6. doi: 10.1042/bj2390233.
Abstract
Production of 14CO2 from an oral load of [1-14C]triolein was greatly decreased (70%) in lactating rats or immediately after (24-48 h) removal of the litter, compared with virgin rats. This decreased oxidation of dietary lipid was accompanied by accumulation of 14C-labelled lipid in lactating mammary gland or adipose tissue (after litter removal). No difference in 14CO2 production between lactating and virgin rats was observed when [1-14C]octanoate was administered. It is concluded that a major factor in this conservation of dietary triacylglycerol is the relative activity of lipoprotein lipase in the tissues.
摘要
与未生育的大鼠相比，哺乳期大鼠或在移除幼崽后立即（24 - 48小时）口服[1 - ¹⁴C]三油酸甘油酯后¹⁴CO₂的生成量大幅减少（70%）。这种膳食脂质氧化的减少伴随着¹⁴C标记的脂质在哺乳期乳腺或脂肪组织（移除幼崽后）中的积累。当给予[1 - ¹⁴C]辛酸时，未观察到哺乳期和未生育大鼠之间¹⁴CO₂生成量的差异。得出的结论是，膳食三酰甘油这种保存现象的一个主要因素是组织中脂蛋白脂肪酶的相对活性。
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