Martínez-García Miguel Angel, Olveira Casilda, Máiz Luis, Girón Rosa M ª, Prados Concepción, de la Rosa David, Blanco Marina, Agustí Alvar
Servicio de Neumología, Hospital Universitario y Politécnico La Fe, Valencia, España.
Servicio de Neumología, Hospital Regional Universitario de Málaga, Málaga, España.
Arch Bronconeumol (Engl Ed). 2019 Aug;55(8):427-433. doi: 10.1016/j.arbres.2019.02.024. Epub 2019 Apr 18.
Most areas of respiratory medicine continue to use an Oslerian approach, based on signs and symptoms, in which the disease is the center of all activity. However, this paradigm is changing. Now that lung diseases have been recognized as heterogeneous and complex, we are moving towards more personalized, precise, patient-oriented medicine. The aim of this review was to define the current state of the knowledge on bronchiectasis, or, more accurately, the bronchiectasis syndrome, as a multidimensional, systemic, heterogeneous, complex disease. We explore the advances that have already been made, and above all the many steps that are still to be taken. We also propose some tools which might facilitate the application of these concepts in clinical practice, and help us continue our journey towards a more holistic view of this disease.
呼吸医学的大多数领域仍在采用基于体征和症状的奥斯勒式方法，其中疾病是所有活动的核心。然而，这种模式正在发生变化。鉴于肺部疾病已被认识到具有异质性和复杂性，我们正朝着更个性化、精确、以患者为导向的医学发展。本综述的目的是界定支气管扩张症，或者更准确地说，支气管扩张综合征作为一种多维、全身性、异质性、复杂疾病的当前知识状态。我们探讨了已经取得的进展，尤其是仍需采取的许多步骤。我们还提出了一些工具，这些工具可能有助于在临床实践中应用这些概念，并帮助我们继续朝着对这种疾病更全面的认识迈进。
