Clinic of Internal Medicine, Södra Älvsborgs Hospital, Borås, Sweden.
Department of Internal Medicine, Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
BMJ Open. 2019 Apr 20;9(4):e024454. doi: 10.1136/bmjopen-2018-024454.
The general aim was to meet the need for empirical comparative studies of health-related quality of life (HRQoL) assessment instruments, by evaluating and comparing the psychometric properties and results of three different, widely used, generic HRQoL instruments in a population sample. The specific aims were to evaluate the subscales of the different instruments that measure the same domain and to assess the association between the HRQoL measures and a single-item self-rated health scale.
An observational cross-sectional study.
A population-based sample from Gothenburg, Sweden, was studied in 2008 in the WHO MONItoring of trends and determinants for CArdiovascular disease.
A total of 414 subjects were included, 77% women, age range 39-78 years.
The Nottingham Health Profile (NHP), the Short Form-36 questionnaire (SF-36), the Psychological General Well-Being Index (PGWB) and a self-rated health scale were used.
Scores were analysed for their psychometric properties, internal consistency (Cronbach's α), construct validity (Spearman's rank correlations and R coefficients) and discriminative ability for the presence of self-rated ill-health.
PGWB and SF-36 had higher Cronbach's α scores than NHP. All correlations calculated between the subscales that were conceptually similar were significant (p<0.01). All subscales could differentiate the presence of self-rated ill-health according to the self-rated health scale (p<0.001). The self-rated health scale correlated strongly with all of the three HRQoL instruments used.
There was a high concordance between the instruments within each domain that was conceptually similar. All three HRQoL instruments (PGWB, SF-36 and NHP) could discriminate the presence of self-rated ill-health. The simple and quick self-rated health scale correlated strongly with the more time-consuming PGWB, SF-36 and NHP. The result supports the existence of a strong association between the self-rated health scale and HRQoL in the general population.
通过评估和比较三种广泛使用的通用健康相关生活质量（HRQoL）评估工具在人群样本中的心理测量特性和结果，满足对 HRQoL 评估工具的实证比较研究的需求。具体目的是评估测量同一领域的不同工具的子量表，并评估 HRQoL 测量与单项自我评定健康量表之间的相关性。
观察性横断面研究。
2008 年在瑞典哥德堡进行了一项基于人群的样本研究，该研究是世界卫生组织监测心血管疾病趋势和决定因素项目的一部分。
共纳入 414 名受试者，其中 77%为女性，年龄 39-78 岁。
使用诺丁汉健康量表（NHP）、36 项简短健康调查量表（SF-36）、心理综合健康指数（PGWB）和单项自我评定健康量表。
对量表的心理测量特性、内部一致性（Cronbach's α）、结构有效性（Spearman 等级相关和 R 系数）以及自我评定不健康状态的判别能力进行了分析。
PGWB 和 SF-36 的 Cronbach's α 评分高于 NHP。概念上相似的子量表之间的所有相关性均具有统计学意义（p<0.01）。所有子量表均能根据自我评定健康量表区分自我评定的健康状况（p<0.001）。自我评定健康量表与使用的三种 HRQoL 工具均具有强烈相关性。
在概念上相似的每个领域内，工具之间具有高度一致性。所有三种 HRQoL 工具（PGWB、SF-36 和 NHP）均能区分自我评定的健康状况。简单快速的自我评定健康量表与更耗时的 PGWB、SF-36 和 NHP 具有强烈相关性。结果支持一般人群中自我评定健康量表与 HRQoL 之间存在强相关性。
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