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职业性吸入纳米颗粒暴露:年轻工人是否被忽视了?

Occupational exposure to inhaled nanoparticles: Are young workers being left in the dust?

机构信息

Institute for Work and Health, University of Lausanne, Epalinges-Lausanne, Switzerland.

Public Health Service, Cantonal Medical Office, Lausanne, Switzerland.

出版信息

J Occup Health. 2019 Sep;61(5):333-338. doi: 10.1002/1348-9585.12056. Epub 2019 Apr 22.

DOI:10.1002/1348-9585.12056
PMID:31006954
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6718838/
Abstract

OBJECTIVES

Occupational exposure to inhaled nanoparticles (NPs) represents a significant concern for worker health. Adolescent workers may face unique risks for exposure and resulting health effects when compared with adult workers.

METHODS

This manuscript discusses key differences in risks for occupational exposures to inhaled NPs and resulting health effects between young workers and adult workers via an examination of both physiological and occupational setting factors.

RESULTS

Previous studies document how adolescents often face distinct and unique exposure scenarios to occupational hazards when compared to adults. Moreover, they also face different and unpredictable health effects because biological functions such as detoxification pathways and neurological mechanisms are still developing well into late adolescence. Early exposure also increases the chances of developing long-latency disease earlier in life. Taken together, adolescents' rapid growth and development encompasses highly dynamic and complex processes. An aggravating factor is that these processes do not necessarily fall in line with legal classifications of adulthood, nor with occupational exposure limits created for adult workers.

CONCLUSIONS

The differences in exposures and health consequences from NPs on young workers are insufficiently understood. Research is needed to better understand what adolescent-specific mitigation strategies may be most suitable to address these risk factors.

摘要

目的

职业性吸入纳米颗粒(NPs)暴露对工人健康构成重大关切。与成年工人相比,青少年工人在暴露和由此产生的健康影响方面可能面临独特的风险。

方法

本文通过考察生理和职业环境因素,讨论了青少年工人与成年工人之间吸入纳米颗粒的职业暴露风险和由此产生的健康影响的关键差异。

结果

先前的研究表明,与成年人相比,青少年在面临职业危害时通常面临独特和独特的暴露情况。此外,由于解毒途径和神经机制等生物功能仍在青春期后期发育,他们还面临着不同且不可预测的健康影响。早期接触也增加了在生命早期更早患上潜伏期疾病的机会。总之,青少年的快速成长和发展涵盖了高度动态和复杂的过程。一个加剧的因素是,这些过程不一定符合成年的法律分类,也不符合为成年工人制定的职业暴露限值。

结论

对于年轻工人来说,纳米颗粒暴露和健康后果的差异尚未得到充分理解。需要研究以更好地了解哪些针对青少年的特定缓解策略可能最适合解决这些风险因素。