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沙特阿拉伯成年人的哮喘控制及预测因素:中东成年哮喘患者人群哮喘管理的流行病学研究结果

Asthma control and predictive factors among adults in Saudi Arabia: Results from the Epidemiological Study on the Management of Asthma in Asthmatic Middle East Adult Population study.

作者信息

Al-Jahdali Hamdan, Wali Siraj, Salem Gamal, Al-Hameed Fahad, Almotair Abdullah, Zeitouni Mohammed, Aref Hassan, Nadama Rufai, Algethami Mohammed M, Al Ghamdy Ahmed, Dihan Tarek

机构信息

McGill University, Québec, Canada.

King Saud University for Health Sciences, Riyadh, KSA.

出版信息

Ann Thorac Med. 2019 Apr-Jun;14(2):148-154. doi: 10.4103/atm.ATM_348_18.

Abstract

CONTEXT

Asthma control is suboptimal in the Middle East and North Africa (MENA).

AIMS

The aim of this study is to assess the level of asthma control in Saudi patients as per the Global Initiative for Asthma 2012 classification and explore its potential predictive factors.

SETTINGS AND DESIGN

Epidemiological Study on the Management of Asthma in Asthmatic Middle East Adult Population (ESMAA) is a multicentric, descriptive, epidemiological study assessing asthma management in the MENA region. In this article, we report the results of patients from Saudi Arabia included in the ESMAA study.

METHODS

Adult patients diagnosed with asthma at least 1 year before study entry were considered for inclusion. Asthma control level and its predictive factors were explored. Treatment adherence and quality of life (QoL) were assessed by MMAS-4 and Short Form 8 Health Survey QoL questionnaires, respectively.

STATISTICAL ANALYSIS USED

Descriptive statistics were done considering two-sided 95% confidence intervals. Logistic regression was used to explore the potential predictive factors of asthma control. All statistical tests were two-sided, and < 0.05 was considered statistically significant.

RESULTS

Data of 1009 patients from Saudi Arabia were analyzed. Less than one-third of patients (30.1%) were found to have controlled asthma with significantly higher QoL. High level of asthma control was reported among male patients and those with high educational level, while age, body mass index, and adherence to treatment were found to have no effect on asthma control.

CONCLUSIONS

Asthma control remains suboptimal among Saudi population. This needs huge efforts to achieve acceptable levels of control and better QoL for asthma patients. Further studies are still needed in Saudi Arabia and the Middle East region.

摘要

背景

中东和北非地区的哮喘控制情况未达最佳水平。

目的

本研究旨在根据《全球哮喘防治创议》2012年分类标准评估沙特患者的哮喘控制水平,并探究其潜在的预测因素。

研究背景与设计

中东成年哮喘患者哮喘管理的流行病学研究(ESMAA)是一项多中心、描述性的流行病学研究,旨在评估中东和北非地区的哮喘管理情况。在本文中,我们报告了ESMAA研究中纳入的沙特患者的结果。

方法

纳入在研究入组前至少已确诊哮喘1年的成年患者。探究哮喘控制水平及其预测因素。分别通过MMAS-4和简短健康调查问卷8来评估治疗依从性和生活质量(QoL)。

所用统计分析方法

采用描述性统计,并考虑双侧95%置信区间。使用逻辑回归来探究哮喘控制的潜在预测因素。所有统计检验均为双侧检验,P<0.05被认为具有统计学意义。

结果

对来自沙特的1009例患者的数据进行了分析。发现不到三分之一的患者(30.1%)哮喘得到控制,且生活质量显著更高。男性患者和高学历患者的哮喘控制水平较高,而年龄、体重指数和治疗依从性对哮喘控制无影响。

结论

沙特人群的哮喘控制仍未达最佳水平。这需要付出巨大努力,以使哮喘患者达到可接受的控制水平并提高生活质量。沙特阿拉伯和中东地区仍需进一步研究。

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