Stevens Lewis, Félix Marie-Anne, Beltran Toni, Braendle Christian, Caurcel Carlos, Fausett Sarah, Fitch David, Frézal Lise, Gosse Charlie, Kaur Taniya, Kiontke Karin, Newton Matthew D, Noble Luke M, Richaud Aurélien, Rockman Matthew V, Sudhaus Walter, Blaxter Mark
Institute of Evolutionary Biology, Ashworth Laboratories, School of Biological Sciences University of Edinburgh Edinburgh EH9 3JT United Kingdom.
Institut de Biologie de l'Ecole Normale Supérieure, Centre National de la Recherche Scientifique, Institut National de la Santé et de la Recherche Médicale, École Normale Supérieure Paris Sciences et Lettres 75005 Paris France.
Evol Lett. 2019 Apr 2;3(2):217-236. doi: 10.1002/evl3.110. eCollection 2019 Apr.
The nematode has been central to the understanding of metazoan biology. However, is but one species among millions and the significance of this important model organism will only be fully revealed if it is placed in a rich evolutionary context. Global sampling efforts have led to the discovery of over 50 putative species from the genus , many of which await formal species description. Here, we present species descriptions for 10 new species. We also present draft genome sequences for nine of these new species, along with a transcriptome assembly for one. We exploit these whole-genome data to reconstruct the phylogeny and use this phylogenetic tree to dissect the evolution of morphology in the genus. We reveal extensive variation in genome size and investigate the molecular processes that underlie this variation. We show unexpected complexity in the evolutionary history of key developmental pathway genes. These new species and the associated genomic resources will be essential in our attempts to understand the evolutionary origins of the model.
线虫对于后生动物生物学的理解至关重要。然而，它只是数百万物种中的一种，只有将这种重要的模式生物置于丰富的进化背景中，其重要性才能得到充分揭示。全球采样工作已导致从该属中发现了50多种假定物种，其中许多有待进行正式的物种描述。在此，我们给出了10个新的[该属线虫名称]物种的描述。我们还给出了其中9个新物种的基因组草图序列，以及一个物种的转录组组装结果。我们利用这些全基因组数据重建了[该属线虫名称]的系统发育，并使用这棵系统发育树剖析该属形态的进化。我们揭示了基因组大小的广泛差异，并研究了造成这种差异的分子过程。我们展示了关键发育途径基因进化历史中意想不到的复杂性。这些新物种以及相关的基因组资源对于我们理解[该属线虫名称]模式的进化起源至关重要。
