理解遗传密码。
Understanding the Genetic Code.
机构信息
Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, California, USA
出版信息
J Bacteriol. 2019 Jul 10;201(15). doi: 10.1128/JB.00091-19. Print 2019 Aug 1.
Abstract
The universal triple-nucleotide genetic code is often viewed as a given, randomly selected through evolution. However, as summarized in this article, many observations and deductions within structural and thermodynamic frameworks help to explain the forces that must have shaped the code during the early evolution of life on Earth.
摘要
通用三联体遗传密码通常被视为一个既定的、通过进化随机选择的。然而，正如本文所总结的，结构和热力学框架内的许多观察和推论有助于解释在地球上生命早期进化过程中必须形成密码的力量。
相似文献
1
Understanding the Genetic Code.理解遗传密码。
J Bacteriol. 2019 Jul 10;201(15). doi: 10.1128/JB.00091-19. Print 2019 Aug 1.
2
An analysis of the metabolic theory of the origin of the genetic code.遗传密码起源的代谢理论分析
J Mol Evol. 1997 May;44(5):473-6. doi: 10.1007/pl00006170.
3
The information capacity of the genetic code: Is the natural code optimal?遗传密码的信息容量：自然密码是最优的吗？
J Theor Biol. 2017 Apr 21;419:227-237. doi: 10.1016/j.jtbi.2017.01.046. Epub 2017 Feb 3.
4
Protein evolution drives the evolution of the genetic code and vice versa.蛋白质进化推动遗传密码的进化，反之亦然。
Biosystems. 1999 Dec;54(1-2):47-64. doi: 10.1016/s0303-2647(99)00058-1.
5
Genetic code.遗传密码
Curr Biol. 2004 Feb 17;14(4):R147.
6
Energy mapping of the genetic code and genomic domains: implications for code evolution and molecular Darwinism.遗传密码和基因组域的能量图谱：对密码进化和分子达尔文主义的影响。
Q Rev Biophys. 2020 Nov 4;53:e11. doi: 10.1017/S0033583520000098.
7
A Non-neutral Origin for Error Minimization in the Origin of the Genetic Code.遗传密码起源中错误最小化的非中性起源。
J Mol Evol. 2018 Dec;86(9):593-597. doi: 10.1007/s00239-018-9871-7. Epub 2018 Oct 25.
8
p-Adic hierarchical properties of the genetic code.遗传密码的p进数层级特性。
Biosystems. 2019 Nov;185:104017. doi: 10.1016/j.biosystems.2019.104017. Epub 2019 Aug 18.
9
A new classification scheme of the genetic code.一种新的遗传密码分类方案。
J Mol Evol. 2004 Nov;59(5):598-605. doi: 10.1007/s00239-004-2650-7.
10
A hardware interpretation of the evolution of the genetic code.遗传密码进化的硬件解释。
Biosystems. 1985;18(2):209-15. doi: 10.1016/0303-2647(85)90072-3.
引用本文的文献
1
SNP and Structural Study of the Notch Superfamily Provides Insights and Novel Pharmacological Targets against the CADASIL Syndrome and Neurodegenerative Diseases.SNP 与 Notch 超家族的结构研究为针对 CADASIL 综合征和神经退行性疾病的新型药物靶点提供了新的见解。
Genes (Basel). 2024 Apr 23;15(5):529. doi: 10.3390/genes15050529.
2
Codon and Reverse Codon: A Theoretical Approach to Reinterpret the Genetic Code Table.密码子与反密码子：重新诠释遗传密码表的理论方法。
Cureus. 2023 Nov 10;15(11):e48598. doi: 10.7759/cureus.48598. eCollection 2023 Nov.
3
The Evolution of Life Is a Road Paved with the DNA Quadruplet Symmetry and the Supersymmetry Genetic Code.生命的进化是一条由 DNA 四重对称和超对称遗传密码铺就的道路。
Int J Mol Sci. 2023 Jul 27;24(15):12029. doi: 10.3390/ijms241512029.
4
Comprehensive functional characterization of SGCB coding variants predicts pathogenicity in limb-girdle muscular dystrophy type R4/2E.全面的 SGCB 编码变异功能特征分析预测肢带型肌营养不良症 R4/2E 的致病性。
J Clin Invest. 2023 Jun 15;133(12):e168156. doi: 10.1172/JCI168156.
5
Flow-Seq Method: Features and Application in Bacterial Translation Studies.Flow-Seq方法：特征及其在细菌翻译研究中的应用
Acta Naturae. 2022 Oct-Dec;14(4):20-37. doi: 10.32607/actanaturae.11820.
6
The Origin of Translation: Bridging the Nucleotides and Peptides.翻译：翻译的起源：连接核苷酸和肽。
Int J Mol Sci. 2022 Dec 22;24(1):197. doi: 10.3390/ijms24010197.
7
Analysis of nested alternate open reading frames and their encoded proteins.嵌套交替开放阅读框及其编码蛋白质的分析。
NAR Genom Bioinform. 2022 Oct 19;4(4):lqac076. doi: 10.1093/nargab/lqac076. eCollection 2022 Dec.
8
Codon usage bias.密码子使用偏好。
Mol Biol Rep. 2022 Jan;49(1):539-565. doi: 10.1007/s11033-021-06749-4. Epub 2021 Nov 25.
9
Learning the Regulatory Code of Gene Expression.学习基因表达的调控密码。
Front Mol Biosci. 2021 Jun 10;8:673363. doi: 10.3389/fmolb.2021.673363. eCollection 2021.
本文引用的文献
1
Considering planetary environments in origin of life studies.考虑行星环境在生命起源研究中的作用。
Nat Commun. 2018 Dec 12;9(1):5170. doi: 10.1038/s41467-018-07493-3.
2
Formyl-methionine as an N-degron of a eukaryotic N-end rule pathway.甲硫氨酸(formyl-methionine)作为真核 N 端规则途径的 N 去稳定基。
Science. 2018 Nov 30;362(6418). doi: 10.1126/science.aat0174. Epub 2018 Nov 8.
3
Modifications and functional genomics of human transfer RNA.人转移 RNA 的修饰和功能基因组学。
Cell Res. 2018 Apr;28(4):395-404. doi: 10.1038/s41422-018-0013-y. Epub 2018 Feb 20.
4
Deciphering pathogenicity and antibiotic resistance islands in methicillin-resistant genomes.解析耐甲氧西林金黄色葡萄球菌基因组中的致病性和抗生素耐药岛。
Open Biol. 2017 Dec;7(12). doi: 10.1098/rsob.170094.
5
On universal coding events in protein biogenesis.关于蛋白质生物合成中的通用编码事件。
Biosystems. 2018 Feb;164:16-25. doi: 10.1016/j.biosystems.2017.10.004. Epub 2017 Oct 10.
6
Codon optimality, bias and usage in translation and mRNA decay.密码子优化、偏性及其在翻译和mRNA降解中的使用
Nat Rev Mol Cell Biol. 2018 Jan;19(1):20-30. doi: 10.1038/nrm.2017.91. Epub 2017 Oct 11.
7
Non-AUG translation: a new start for protein synthesis in eukaryotes.非AUG翻译：真核生物蛋白质合成的新起点。
Genes Dev. 2017 Sep 1;31(17):1717-1731. doi: 10.1101/gad.305250.117.
8
IF2 and unique features of initiator tRNA help establish the translational reading frame.IF2 和起始 tRNA 的独特特征有助于建立翻译阅读框。
RNA Biol. 2018;15(4-5):604-613. doi: 10.1080/15476286.2017.1379636. Epub 2017 Nov 13.
9
A new and updated resource for codon usage tables.密码子使用表的全新更新资源。
BMC Bioinformatics. 2017 Sep 2;18(1):391. doi: 10.1186/s12859-017-1793-7.
10
Origin and Evolution of the Universal Genetic Code.通用遗传密码的起源与演化。
Annu Rev Genet. 2017 Nov 27;51:45-62. doi: 10.1146/annurev-genet-120116-024713. Epub 2017 Aug 30.
Zotero 插件