Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Hypertens Res. 2019 Oct;42(10):1599-1605. doi: 10.1038/s41440-019-0264-0. Epub 2019 Apr 24.
Based on the obesity paradox, people with a normal body mass index (BMI) may have a higher risk of mortality than those with a BMI that falls within the obese range. Despite the availability of other anthropometric measures, obesity is commonly evaluated based on BMI. A body shape index (ABSI) and body roundness index (BRI) have recently been proposed as new anthropometric measures that are calculated with height, weight, and waist circumference. This study investigated the associations between the traditional and new body composition indices and arterial stiffness using the brachial-ankle pulse wave velocity (baPWV). Overall, 3512 individuals (1228 men and 2284 women) were enrolled and were divided into two groups according to BMI. Multiple regression analysis was performed to assess the relationship between baPWV and body composition. baPWV was significantly associated with ABSI (β = 0.087, p = 0.002), visceral adipose tissue (VAT; β = 0.081, p = 0.002), and the visceral/subcutaneous adipose tissue (VAT/SAT) ratio (β = 0.108, p < 0.001) in non-obese men. In non-obese women, baPWV was significantly associated with several variables but not the VAT/SAT ratio. Similarly, baPWV was significantly associated with BMI (β = 0.103, p = 0.038), BRI (β = 0.104, p = 0.036), VAT (β = 0.167, p = 0.001), and the VAT/SAT ratio (β = 0.106, p = 0.028) in obese women. ABSI can be used with high accuracy to evaluate fat distribution in non-obese men to predict arterial stiffness. However, the BRI should be used in addition to BMI to assess the body composition of women more accurately. ABSI and the BRI can be used to identify predictors of vascular remodeling or organic vascular dysfunction.
基于肥胖悖论，身体质量指数（BMI）正常的人可能比处于肥胖范围内的 BMI 人群有更高的死亡率。尽管有其他人体测量指标可用，但肥胖通常是根据 BMI 来评估的。身体形状指数（ABSI）和身体圆润指数（BRI）最近被提议作为新的人体测量指标，这些指标是通过身高、体重和腰围计算出来的。本研究使用肱踝脉搏波速度（baPWV）研究了传统和新的身体成分指标与动脉僵硬之间的关系。总共纳入了 3512 名个体（1228 名男性和 2284 名女性），并根据 BMI 将其分为两组。进行多元回归分析以评估 baPWV 与身体成分之间的关系。baPWV 与 ABSI（β=0.087，p=0.002）、内脏脂肪组织（VAT；β=0.081，p=0.002）和内脏/皮下脂肪组织（VAT/SAT）比值（β=0.108，p<0.001）显著相关在非肥胖男性中。在非肥胖女性中，baPWV 与多个变量显著相关，但与 VAT/SAT 比值无关。同样，baPWV 与 BMI（β=0.103，p=0.038）、BRI（β=0.104，p=0.036）、VAT（β=0.167，p=0.001）和 VAT/SAT 比值（β=0.106，p=0.028）显著相关肥胖女性。ABSI 可用于准确评估非肥胖男性的脂肪分布，以预测动脉僵硬。然而，应该使用 BRI 来更准确地评估女性的身体成分。ABSI 和 BRI 可用于识别血管重塑或有机血管功能障碍的预测因子。
