Department of Ophthalmology, College of Medicine, Chung-Ang University Hospital, Seoul, Republic of Korea.
Departement of Ophthalmology, Konyang University Hospital, Daejeon, Republic of Korea.
Eye (Lond). 2019 Oct;33(10):1540-1546. doi: 10.1038/s41433-019-0439-6. Epub 2019 Apr 24.
To evaluate the impact of the age of onset of low vision on patients' vision-related quality of life (VR-QoL) and mental health.
Low-vision patients who visited Chung-Ang University hospital from January 2012 to December 2014 were included. Patients were divided into the congenital low-vision (CLV) and acquired low-vision (ALV) groups according to the age of disease onset. People with normal visual function comprised the control group. VR-QoL was estimated with the National Eye Institute Visual Function Questionnaire (NEI VFQ-25), while mental health was assessed through the Beck Depression Inventory (BDI) and the Beck Anxiety Inventory (BAI). The mean scores of each questionnaire were compared between the groups in independent t-tests.
Overall, 125 low-vision patients (55 CLV and 70 ALV) and 71 control subjects were included. Although the subscale and composite scores of the NEI VFQ-25 were lower in the ALV group than in the CLV group, the differences were not significant. However, the BDI and BAI scores were significantly higher in the ALV group than in the CLV group (12.07 ± 11.97 vs. 7.67 ± 9.04, P = 0.021; 9.11 ± 10.51 vs. 5.69 ± 6.85, P = 0.030, respectively). Also, the number of patients requiring expert consultation for depression was higher in the ALV group than in the CLV group (P = 0.010).
ALV patients have more vulnerable mental health states than CLV patients. Therefore, assessment of the age of onset of low vision and mental health plays a critical role in successful rehabilitation.
评估低视力发病年龄对患者视功能相关生活质量（VR-QoL）和心理健康的影响。
纳入 2012 年 1 月至 2014 年 12 月期间在忠南大学医院就诊的低视力患者。根据疾病发病年龄，将患者分为先天性低视力（CLV）和获得性低视力（ALV）组。正常视力人群为对照组。采用国家眼科研究所视功能问卷（NEI VFQ-25）评估 VR-QoL，采用贝克抑郁量表（BDI）和贝克焦虑量表（BAI）评估心理健康。采用独立 t 检验比较各组间各问卷的平均得分。
共纳入 125 例低视力患者（55 例 CLV 和 70 例 ALV）和 71 例对照组。虽然 ALV 组的 NEI VFQ-25 各子量表和综合评分均低于 CLV 组，但差异无统计学意义。然而，ALV 组的 BDI 和 BAI 评分明显高于 CLV 组（12.07±11.97 比 7.67±9.04，P=0.021；9.11±10.51 比 5.69±6.85，P=0.030）。此外，ALV 组需要专家咨询抑郁的患者人数多于 CLV 组（P=0.010）。
ALV 患者的心理健康状态比 CLV 患者更为脆弱。因此，评估低视力的发病年龄和心理健康对视功能康复的成功至关重要。
