Beamer Laura Curr, Grant Marcia
School of Nursing & Health Studies, Northern Illinois University, DeKalb, IL, USA.
College of Nursing, University of Utah, Salt Lake City, UT, USA.
Breast Cancer (Auckl). 2019 Apr 12;13:1178223419835547. doi: 10.1177/1178223419835547. eCollection 2019.
The purpose of this study is to report the initial validation process for using the Dermatology Life Quality Index (DLQI) for radiodermatitis of the breast.
This is an additional analysis of a study designed to report a longitudinal study in skin-related and global quality of life in women with breast radiodermatitis. A total of 40 participants completed the DLQI instrument weekly while receiving external radiotherapy of the female breast. At week 5 on treatment, 31 (78%) participants provided narrative feedback on how each DLQI item affected her life. Agreement between participant DLQI numerical ratings and narrative feedback on items was assessed. Construct validity was estimated using principal component analysis (PCA). Internal consistency of the DLQI was assessed using Cronbach alpha.
Percentage of agreement between participant DLQI ratings and narratives ranged from 71% to 98%. Each participant responded "no" to the work and study item leading to zero variance and removal from our analyses. Principal component analysis supported the inclusion of all of the remaining items. The DLQI with nine remaining items demonstrated moderately good internal consistency (α = .69).
The results of our examination of the DLQI when used for breast radiodermatitis are promising. Next steps include additional larger studies among more diverse populations.
本研究旨在报告将皮肤病生活质量指数(DLQI)用于乳腺放射性皮炎的初步验证过程。
这是一项对旨在报告乳腺放射性皮炎女性患者皮肤相关及整体生活质量纵向研究的额外分析。共有40名参与者在接受女性乳腺外照射放疗期间每周完成DLQI量表。在治疗第5周时,31名(78%)参与者就DLQI的每个项目如何影响其生活提供了叙述性反馈。评估参与者DLQI数值评分与项目叙述性反馈之间的一致性。使用主成分分析(PCA)估计结构效度。使用Cronbach α评估DLQI的内部一致性。
参与者DLQI评分与叙述之间的一致率在71%至98%之间。每位参与者对工作和学习项目的回答均为“否”,导致方差为零并从我们的分析中剔除。主成分分析支持纳入所有其余项目。剩余九个项目的DLQI显示出中等良好的内部一致性(α = 0.69)。
我们对DLQI用于乳腺放射性皮炎的研究结果很有前景。下一步包括在更多样化人群中开展更多更大规模的研究。