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经皮经肝内镜会师术治疗难治性胆管梗阻安全有效。

Percutaneous-transhepatic-endoscopic rendezvous procedures are effective and safe in patients with refractory bile duct obstruction.

机构信息

Department of Medicine B for Gastroenterology and Hepatology, University Hospital Münster, Münster, Germany.

Department of Internal Medicine, Evangelisches Krankenhaus Düsseldorf, Düsseldorf, Germany.

出版信息

United European Gastroenterol J. 2019 Apr;7(3):397-404. doi: 10.1177/2050640619825949. Epub 2019 Jan 17.

Abstract

BACKGROUND

Percutaneous-transhepatic-endoscopic rendezvous procedures (PTE-RVs) are rescue approaches used to facilitate biliary drainage.

OBJECTIVE

The objective of this article is to evaluate the safety and the technical success of PTE-RVs in comparison with those of percutaneous transhepatic cholangiographies (PTCs).

METHODS

Percutaneous procedures performed over a 10-year period were retrospectively analyzed in a single-center cohort. Examinations were performed because of a previous or expected failure of standard endoscopic methods including endoscopic retrograde cholangiography (ERC) or balloon-assisted ERC to achieve biliary access.

RESULTS

In total, 553 percutaneous procedures including 163 PTE-RVs and 390 PTCs were performed. Overall, 71.3% of the patients suffered from malignant disease with pancreas-carcinoma (32.8%) and cholangio-carcinoma (19.0%) as the most frequent, while 28.7% of the patients suffered from benign disease. Many patients had a postoperative change in bowel anatomy (50.8%).PTC had a higher technical success rate (89.7%); however, the technical success rate of PTE-RVs was still high (80.4%;  < 0.003). Overall complications occurred in 23.5% of all procedures. Significantly fewer complications occurred after performing PTE-RVs than after PTCs (16.6% vs 26.4%;  = 0.037).

CONCLUSION

Beside a high technical efficacy of PTE-RVs, significantly fewer complications occur following PTE-RVs than following PTCs; thus, PTE-RV should be preferred over PTC alone in selected patients.

摘要

背景

经皮经肝内镜联合经皮经肝胆道引流术(PTE-RV)是一种用于辅助胆道引流的抢救方法。

目的

本文旨在评估与经皮经肝胆道造影术(PTC)相比,PTE-RV 的安全性和技术成功率。

方法

回顾性分析了一家中心 10 年间的经皮操作,这些检查是由于标准内镜方法(包括内镜逆行胆胰管造影术(ERC)或球囊辅助 ERC)预计或之前失败,无法实现胆道进入而进行的。

结果

共进行了 553 例经皮操作,包括 163 例 PTE-RV 和 390 例 PTC。总体而言,71.3%的患者患有恶性疾病,其中胰腺癌(32.8%)和胆管癌(19.0%)最为常见,而 28.7%的患者患有良性疾病。许多患者术后肠解剖结构发生改变(50.8%)。PTC 的技术成功率更高(89.7%);然而,PTE-RV 的技术成功率仍然很高(80.4%;<0.003)。所有操作中,总并发症发生率为 23.5%。与 PTC 相比,PTE-RV 后并发症发生率显著降低(16.6%比 26.4%;=0.037)。

结论

除了 PTE-RV 的高技术疗效外,与 PTC 相比,PTE-RV 后并发症发生率显著降低;因此,在选择患者时,应优先选择 PTE-RV 而不是单独进行 PTC。

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