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测量泪膜破裂时间在隐形眼镜配镜中的应用。

The utility of measuring tear film break-up time for prescribing contact lenses.

机构信息

Department of Biomedical Engineering, Wroclaw University of Science and Technology, Poland.

Department of Biomedical Engineering, Wroclaw University of Science and Technology, Poland; Department of Neurosciences, Catholic University of Leuven, Belgium.

出版信息

Cont Lens Anterior Eye. 2018 Feb;41(1):105-109. doi: 10.1016/j.clae.2017.08.003. Epub 2017 Aug 30.

Abstract

PURPOSE

To evaluate the clinical value of non-invasive keratograph tear film breakup time (NIKBUT) in the assessment of pre-corneal and pre-lens tear film quality for prescribing contact lenses (CLs).

METHODS

Forty-six subjects aged 25.5±4.3 (mean±standard deviation) years were recruited. Visual acuity (VA), anterior eye health checks and NIKBUT were evaluated. On the following day, subjects were fitted with a daily Silicon Hydrogel (SiHy) CL in one eye and a Hydrogel (Hy) CL in the other. After four hours one material for both eyes was chosen based on a qualitative analysis which included VA, CL fitting and comfort. Information about the first and the mean NIKBUT was then contrasted against the prescription decision.

RESULTS

Thirty-four subjects were fitted with SiHy and twelve with Hy CL. No statistically significant differences were found for both NIKBUT parameters between left and right eye at baseline (p=0.38 and p=0.50, respectively) and post four hours of CL wear (p=0.61 and p=0.06). The chosen lens did not always correspond to longer NIKBUT. In 39.1% and 34.8% of cases (i.e., 18 and 16 out of 46), there was a match between prescription decision and the first and the mean NIKBUT results, respectively.

CONCLUSIONS

Although there is no evidence whether tear film surface quality measurement has a superior diagnostic values compared to other traditional clinical measures used in practice, NIKBUT measurements have provided additional information that could be of interest during CL fit.

摘要

目的

评估无创性角膜描记泪膜破裂时间(NIKBUT)在评估接触镜(CL)处方前角膜前和前透镜泪膜质量中的临床价值。

方法

招募了 46 名年龄为 25.5±4.3(平均值±标准差)岁的受试者。评估了视力(VA)、眼前部健康检查和 NIKBUT。次日,在一只眼上配戴日抛硅水凝胶(SiHy)CL,另一只眼配戴水凝胶(Hy)CL。四小时后,根据 VA、CL 适配和舒适度的定性分析,选择两种材料中的一种。然后将前两个和平均 NIKBUT 的信息与处方决策进行对比。

结果

34 名受试者配戴 SiHy CL,12 名配戴 Hy CL。在基线时(p=0.38 和 p=0.50)和戴 CL 四小时后(p=0.61 和 p=0.06),左右眼的两个 NIKBUT 参数均无统计学差异。所选镜片并不总是与较长的 NIKBUT 相对应。在 39.1%和 34.8%的情况下(即 46 例中的 18 例和 16 例),处方决策与第一个和平均 NIKBUT 结果之间存在匹配。

结论

尽管尚无证据表明泪膜表面质量测量是否比其他传统临床测量在实践中有更高的诊断价值,但 NIKBUT 测量提供了额外的信息,在 CL 适配期间可能会引起关注。

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