Department of Bioengineering, Faculty of Engineering, Integral University, Lucknow, UP, 226026, India.
Advanced Center of Bioengineering and Bioinformatics, Integral Information and Research Centre, Integral University, Lucknow, UP, 226026, India.
Environ Sci Pollut Res Int. 2020 Jun;27(16):19127-19141. doi: 10.1007/s11356-019-05152-8. Epub 2019 Apr 25.
Empowering role of nanoinformatics in design and elucidation of nanoparticles for effective cancer treatment has made this field a fascinating area for researchers, inspiring them to enhance up the quality and efficacy of existing anticancer medicines. Theoretical and computational modeling is being seen as a forefront solution for problems related to surface chemistry, optimized geometry, or other properties in nanoparticle designing and drug delivery. The current review aims to acquaint with the insight story of the incubation of in silico tools and techniques in nanotechnology to develop better anticancer nanomedicines. The review also recapitulates the assets and liabilities of this field and present an outline of existing inventiveness and endeavors of nanoinformatics. We propose how nanoinformatics could hasten up the advancements in anticancer nanomedicines through use of computational tools, nanoparticles repositories & various modeling and simulation methods.
纳米信息学在设计和阐明用于有效癌症治疗的纳米粒子方面的赋权作用，使该领域成为研究人员关注的焦点，激发他们提高现有抗癌药物的质量和疗效。理论和计算建模被视为解决与纳米粒子设计和药物输送相关的表面化学、优化几何形状或其他特性的前沿解决方案。本综述旨在介绍计算工具和技术在纳米技术中孵化以开发更好的抗癌纳米药物的内幕故事。该综述还总结了该领域的优缺点，并概述了纳米信息学的现有创造力和努力。我们提出了纳米信息学如何通过使用计算工具、纳米粒子库以及各种建模和模拟方法来加速抗癌纳米药物的进展。
