Department of Ophthalmology, Goethe University, Frankfurt am Main, Germany.
Eye (Lond). 2019 Oct;33(10):1556-1563. doi: 10.1038/s41433-019-0443-x. Epub 2019 Apr 26.
To evaluate the visual performance of an extended depth of focus (EDOF) intraocular lens (IOL) for patient selection.
This prospective non-comparative case series evaluated fifty-two eyes (26 patients) after bilateral implantation of the Tecnis Symfony IOL. Exclusion criteria were previous ocular surgeries, corneal astigmatism of >1.5 diopter, and ocular pathologies or corneal abnormalities. Uncorrected (UCVA) and distance-corrected (DCVA) visual acuity (VA) in 4 m, 80 cm, 60 cm and 40 cm (logMAR), defocus curve, contrast sensitivity (CS) and a questionnaire on subjective quality of vision (QoV) were assessed after 3 months.
UCVA was -0.02 ± 0.071 logMAR at 4 m, 0.01 ± 0.077 logMAR at 80 cm, 0.08 ± 0.187 logMAR at 60 cm and 0.22 ± 0.153 logMAR at 40 cm. Defocus curve testing showed a flat VA range from 0.00 to -1.50 D (-0.05-0.02 logMAR). At near distance from -2.0 to -2.5 D a dip of DCVA was observed (0.14-0.28 logMAR). CS under photopic and mesopic conditions without and with glare was 1.56 logCS, 0.86 logCS, 0.78 logCS, respectively. Spectacle independence was achieved in 100% for distance and intermediate vision and 71% of patients at near distance.
This EDOF IOL provides excellent intermediate and far (<0.1 logMAR) and acceptable near UCVA (<0.3 logMAR). Defocus curve testing confirmed an EDOF between far and intermediate distance and showed a dip at near distance. It provides good QoV, CS, high spectacle independence, perception of few optical phenomena, and particularly good night-driving capabilities.
评估具有扩展景深（EDOF）的人工晶状体（IOL）的视觉性能，以选择患者。
本前瞻性非对照病例系列研究评估了 52 只眼（26 例患者）在双侧植入 Tecnis Symfony IOL 后的情况。排除标准为既往眼部手术、＞1.5 屈光度的角膜散光和眼部病变或角膜异常。术后 3 个月评估未矫正视力（UCVA）和距离矫正视力（DCVA）在 4m、80cm、60cm 和 40cm（logMAR）、离焦曲线、对比敏感度（CS）和主观视觉质量问卷（QoV）。
UCVA 在 4m 时为-0.02±0.071 logMAR，在 80cm 时为 0.01±0.077 logMAR，在 60cm 时为 0.08±0.187 logMAR，在 40cm 时为 0.22±0.153 logMAR。离焦曲线测试显示 0.00 至-1.50 D（-0.05-0.02 logMAR）的平坦 VA 范围。在近距从-2.0 至-2.5 D 时观察到 DCVA 下降（0.14-0.28 logMAR）。在无眩光和有眩光的明视和中视条件下 CS 分别为 1.56 logCS、0.86 logCS、0.78 logCS。在距离和中间视力方面，100%的患者达到了不戴眼镜的状态，71%的患者在近距离达到了不戴眼镜的状态。
该 EDOF IOL 提供了极好的中间和远距（＜0.1 logMAR）和可接受的近距 UCVA（＜0.3 logMAR）。离焦曲线测试证实了远距和中距之间的 EDOF，并在近距时显示出下降。它提供了良好的 QoV、CS、高的眼镜独立性、较少的光学现象感知，特别是良好的夜间驾驶能力。
