Periodontology Unit, UCL Eastman Dental Institute and Hospital, University College London, 256 Gray's Inn Road, London, WC1X 8LD, UK.
Periodontology Unit, Faculty of Medicine and Odontology, University of Santiago de Compostela, Medical-Surgical Dentistry (OMEQUI) Research Group, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain.
Odontology. 2019 Oct;107(4):530-535. doi: 10.1007/s10266-019-00430-w. Epub 2019 Apr 27.
The aim of this study was to evaluate self-reported periodontitis (PD) prevalence in migraineurs as well as to investigate the association between both diseases. A cross-sectional survey was carried out including patients diagnosed with migraine attending 12 Spanish Headache Units. We determined diagnosis of PD administering a validated self-reported questionnaire. Socio-demographic, clinical and medical information, comorbidities, daily habits, migraine characteristics and medication were collected using a questionnaire. Of the 651 consecutive migraineurs included in the study, 393 suffered from chronic migraine (CM). Self-reported PD was detected in 327 patients with migraine (50.2%). Migraineurs with self-reported PD were significantly older and had a previous history of fibromyalgia, stress, anxiety, depression, and allodynia (all P < 0.001). Additionally, this group of patients consumed more topiramate (P = 0.008) and simple analgesics (P < 0.001) than patients with migraine and without self-reported PD. Also, they were less active physically and belonged to a low education level (both P < 0.001). Prevalence of self-reported PD was significantly higher in chronic migraineurs compared to those diagnosed with episodic migraine (EM) (53.9% vs. 44.6%, P = 0.019). Logistic regression analyses showed that self-reported PD was associated with CM (OR 1.456; 95% CI 1.062-1.997, P = 0.020). However, after adjusting for significant confounders, the association was attenuated (OR 1.100; 95% CI 0.784-1.543, P = 0.581). We concluded that self-reported PD was significantly more frequent in CM compared to EM. Self-reported PD was associated with the presence of CM, although some comorbidities shared by both diseases could have an effect on this association.
本研究旨在评估偏头痛患者中自我报告的牙周炎（PD）患病率，并探讨这两种疾病之间的关联。进行了一项横断面调查，包括在 12 家西班牙头痛单位就诊的偏头痛患者。我们通过一份经过验证的自我报告问卷来确定 PD 的诊断。使用问卷收集了社会人口统计学、临床和医学信息、合并症、日常习惯、偏头痛特征和药物使用情况。在纳入研究的 651 例连续偏头痛患者中，393 例患有慢性偏头痛（CM）。有偏头痛的患者中，327 例（50.2%）自我报告 PD。患有自我报告 PD 的偏头痛患者年龄明显更大，且有纤维肌痛、压力、焦虑、抑郁和感觉异常的既往病史（均 P<0.001）。此外，与没有自我报告 PD 的偏头痛患者相比，该组患者服用更多的托吡酯（P=0.008）和简单的镇痛药（P<0.001）。此外，他们的身体活动较少，且受教育程度较低（均 P<0.001）。与发作性偏头痛患者相比，慢性偏头痛患者自我报告 PD 的患病率显著更高（53.9%比 44.6%，P=0.019）。逻辑回归分析显示，自我报告 PD 与 CM 相关（OR 1.456；95%CI 1.062-1.997，P=0.020）。然而，在校正了显著的混杂因素后，这种关联减弱了（OR 1.100；95%CI 0.784-1.543，P=0.581）。我们得出结论，与 EM 相比，CM 患者自我报告 PD 的发生率显著更高。自我报告 PD 与 CM 的存在相关，尽管这两种疾病共有的一些合并症可能对这种关联有影响。
