Sabrina Brizee, Diederik A. Bleijs, Harold H. J. L. van den Berg, Evelien Kampert, and Mark W. J. van Passel are with the National Institute for Public Health and the Environment, Bilthoven, The Netherlands. Musa Kwehangana, Collins Mwesigwa, and Maxwell Otim Onapa are with the Uganda National Council for Science and Technology, Kampala, Uganda. Milton Wetaka Makoba and Issa Makumbi are with the Emergency Operations Centre, Ministry of Health, Kampala, Uganda. Atek Kagirita is with the Central Public Health Laboratories, Ministry of Health, Kampala, Uganda. Francis Kakooza is with the Infectious Disease Institute, Makarere University, Kampala, Uganda.
Health Secur. 2019 May/Jun;17(3):169-173. doi: 10.1089/hs.2018.0112. Epub 2019 Apr 27.
One of the challenges of global biosecurity is to protect and control dangerous pathogens from unauthorized access and intentional release. A practical and feasible option to protect life science institutes against theft and sabotage, and secure their biological materials against misuse, is to establish a national electronic database with a comprehensive overview of the locations of all controlled dangerous pathogens in a country. This national database could be used as an instrument to secure and account for dangerous pathogens in a country, but it could also assist in establishing a biosecurity assessing and monitoring system for laboratories that work with these controlled biological agents. The Republic of Uganda is one of the first countries, prompted by the World Health Organization's (WHO's) Joint External Evaluation (JEE), to implement a national electronic database that assembles information collected from relevant Ugandan laboratories. This Ugandan Inventory of Dangerous Pathogens is different from an institute-specific pathogen inventory system, as it is intended to store the information collected from laboratories in the country working with dangerous pathogens in 1 centralized secure location. The Uganda National Council for Science and Technology (UNCST) has coordinated the implementation of the Ugandan national inventory. The inventory was recognized by the WHO JEE as contributing to Uganda's developed capacities regarding biosafety and biosecurity. This article describes the steps in implementing Uganda's National Inventory of Dangerous Pathogens. In addition, it presents a straightforward approach that can be adapted by other countries that aim to enhance their biosecurity capacities.
全球生物安全面临的挑战之一是防止危险病原体未经授权进入和故意释放。保护生命科学研究所免受盗窃和破坏，确保其生物材料不被滥用的一种实用且可行的选择是建立一个国家电子数据库，全面概述一个国家所有受控制危险病原体的位置。这个国家数据库可以作为一种工具，用于保护和核算一个国家的危险病原体，但它也可以协助建立一个用于处理这些受控制生物制剂的实验室的生物安全评估和监测系统。乌干达共和国是在世界卫生组织（WHO）联合外部评估（JEE）的推动下，率先实施国家电子数据库的国家之一，该数据库汇集了从相关乌干达实验室收集的信息。这种乌干达危险病原体清单与特定机构的病原体清单系统不同，因为它旨在将从该国从事危险病原体工作的实验室收集的信息存储在一个集中安全的位置。乌干达国家科学技术委员会（UNCST）协调了乌干达国家清单的实施。该清单得到了世卫组织 JEE 的认可，认为它有助于乌干达在生物安全和生物安保方面的能力发展。本文介绍了实施乌干达国家危险病原体清单的步骤。此外，它还提出了一种简单直接的方法，其他旨在增强其生物安保能力的国家也可以采用这种方法。
