Laboratory of Research in Respiratory Physiotherapy (LFIP), Department of Physiotherapy, Universidade Estadual de Londrina (UEL), Londrina, Paraná, Brazil.
Department of Rehabilitation Sciences, Katholieke Universiteit Leuven, Leuven, Belgium.
PLoS One. 2019 Apr 30;14(4):e0215544. doi: 10.1371/journal.pone.0215544. eCollection 2019.
To provide a Portuguese version of the Multidimensional Dyspnea Profile (MDP), investigating its validity and reliability in Brazilian patients with COPD.
This was a cross-sectional study for translation and linguist validation of the Portuguese MDP version for patients with COPD. The process occurred according to the protocol of Mapi Research Trust, Lyon, France. Three scores of MDP were used for the analysis: the immediate unpleasantness of dyspnea (A1); the "immediate perception domain" (S) (sum of A1 plus the sensory descriptors) and the "emotional response domain" (A2) (sum of the emotional descriptors). The questionnaires COPD assessment Test (CAT), Hospital Anxiety and Depression scale (HADS) and Medical Research Council scale (MRC) were used as anchors to investigate MDP's validity. Internal consistency was assessed with Cronbach's alpha. Test-retest reliability was assessed with intraclass correlation coefficient (ICC) and concurrent validity was assessed with Spearman correlation coefficients.
Thirty patients with moderate-severe COPD were studied for MDP's validation analysis (43% male, 63±8years, body mass index [BMI] 27±6Kg/m2, forced expiratory volume in the first second [FEV1] 48±15%predicted, six-minute walking test [6MWT] 464±84m and 84±16%predicted), whereas 10 patients were excluded from the test-retest reliability analysis due to missing data, resulting in a sample of 20 subjects for this purpose (50% male, 62±8years, BMI 27±6Kg/m2, FEV1 48±15%predicted, 6MWT 452±93m and 82±19%predicted). Both samples were similar regarding general characteristics (P>0,05 for all variables). MDP presented strong correlations, i.e., ICC intra-rater: A1: 0.77 (0.48-0.90), S: 0.78 (0.52-0.91), and A2: 0.85 (0.66-0.94), with high internal consistency (Cronbach's α 0.86, 0.88 and 0.92 respectively); and ICC inter-rater: A1: 0.74 (0.46-0.89), S: 0.75 (0.48-0.89) and A2: 0.91 (0.78-0.96) with Cronbach's α 0.85, 0.86 and 0.95 respectively.
The Portuguese version of the MDP is the first valid and reliable instrument to assess dyspnea multidimensionally in Portuguese-speaking patients with COPD.
提供多维呼吸困难量表（MDP）的葡萄牙语版本，评估其在巴西 COPD 患者中的有效性和可靠性。
这是一项针对 COPD 患者进行 MDP 葡萄牙语版本翻译和语言验证的横断面研究。该过程按照法国里昂 Mapi 研究信托基金会的方案进行。MDP 的三个评分用于分析：呼吸困难的即时不愉快（A1）；“即时感知域”（S）（A1 加上感觉描述符的总和）和“情绪反应域”（A2）（情绪描述符的总和）。COPD 评估测试（CAT）、医院焦虑和抑郁量表（HADS）和医学研究委员会量表（MRC）被用作调查 MDP 有效性的指标。内部一致性用 Cronbach 的 alpha 进行评估。测试-重测信度用组内相关系数（ICC）进行评估，同时效度用 Spearman 相关系数进行评估。
对 30 名中重度 COPD 患者进行 MDP 验证分析（43%为男性，63±8 岁，体重指数[BMI]27±6kg/m2，第一秒用力呼气量[FEV1]48±15%预测值，6 分钟步行试验[6MWT]464±84m，预测值 84±16%），但由于数据缺失，10 名患者被排除在测试-重测信度分析之外，因此，为此目的选择了 20 名患者（50%为男性，62±8 岁，BMI 27±6kg/m2，FEV1 48±15%预测值，6MWT 452±93m，预测值 82±19%）。两个样本在一般特征方面相似（所有变量 P>0.05）。MDP 呈现出较强的相关性，即内部评估者的 ICC：A1：0.77（0.48-0.90），S：0.78（0.52-0.91），A2：0.85（0.66-0.94），具有较高的内部一致性（Cronbach's α 分别为 0.86、0.88 和 0.92）；以及外部评估者的 ICC：A1：0.74（0.46-0.89），S：0.75（0.48-0.89）和 A2：0.91（0.78-0.96），Cronbach's α 分别为 0.85、0.86 和 0.95。
MDP 的葡萄牙语版本是评估葡萄牙语 COPD 患者呼吸困难的第一个有效且可靠的多维工具。
