Ghafournia Maryam, Tehrani Maryam Hajnorouzali, Nekouei Afsaneh, Faghihian Reyhaneh, Mohammadpour Mehrnaz, Feiz Atiyeh
Dental Research Center, Department of Pediatric Dentistry, School of Dentistry, Isfahan University of Medical Sciences, Shahrekord, Iran.
Department of Pediatric Dentistry, Dental School, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Dent Res J (Isfahan). 2019 May-Jun;16(3):166-171.
Dentin hypersensitivity (DH) is a common problem characterized by a short, sharp pain. Reduction of dentin permeability by occluding dentin tubules is considered as a method for treating DH. Many substances are available to decrease hypersensitivity. The aim of this study is to evaluate the ability of three different remineralizing agents for occluding dentinal tubules in comparison with positive and negative controls.
In this scanning electron microscopic (SEM) study, 75 extracted premolars were cut into crown and root fragments with a bur and divided into five groups: group 1: Sodium fluoride 5% varnish was applied (positive control), Group 2: No treatment (negative control), Group 3: Treated with Remin Pro (contains hydroxyapatite and fluoride), Group 4: Treated with MI paste (contains casein phosphopeptide-amorphous calcium phosphate [CPP-ACP]) and Group 5: Treated with GC tooth mousse (contains CPP-ACP). SEM images were obtained and mean tubular diameter was measured in each group. One-way ANOVA and Duncan's tests were used for statistical analysis. A significant level of α = 0.05 was set for comparison between the groups.
Statistically significant difference was observed between Group 2 (negative control) and other four groups ( < 0.05). There was no significant difference between Groups 1, 3, 4, and 5 ( > 0.05).
Under the limitations of the present study, it can be concluded that the application of a CPP-ACP paste as well as a paste which contains fluoride is effective on reduction of dentin permeability.
牙本质过敏症（DH）是一种常见问题，其特征为短暂、尖锐的疼痛。通过封闭牙本质小管来降低牙本质通透性被认为是一种治疗DH的方法。有许多物质可用于降低过敏反应。本研究的目的是评估三种不同再矿化剂与阳性和阴性对照相比封闭牙本质小管的能力。
在这项扫描电子显微镜（SEM）研究中，用牙钻将75颗拔除的前磨牙切成冠部和根部碎片，并分为五组：第1组：应用5%氟化钠清漆（阳性对照），第2组：不进行处理（阴性对照），第3组：用Remin Pro（含羟基磷灰石和氟化物）处理，第4组：用MI糊剂（含酪蛋白磷酸肽 - 无定形磷酸钙[CPP - ACP]）处理，第5组：用GC护齿泡沫（含CPP - ACP）处理。获取SEM图像并测量每组的平均小管直径。采用单因素方差分析和邓肯检验进行统计分析。设定α = 0.05的显著水平用于组间比较。
在第2组（阴性对照）与其他四组之间观察到统计学上的显著差异（<0.05）。第1、3、4和5组之间无显著差异（>0.05）。
在本研究的局限性下，可以得出结论，应用含CPP - ACP的糊剂以及含氟糊剂对降低牙本质通透性有效。
