Silymarin in the treatment of liver diseases: What is the clinical evidence?
作者信息
Ferenci Peter
机构信息
Internal Medicine 3, Department of Gastroenterology and Hepatology Medical University of Vienna Vienna Austria.
出版信息
Clin Liver Dis (Hoboken). 2016 Jan 29;7(1):8-10. doi: 10.1002/cld.522. eCollection 2016 Jan.
Abstract
摘要
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Silymarin in the treatment of liver diseases: What is the clinical evidence?水飞蓟素治疗肝脏疾病：临床证据有哪些？
Clin Liver Dis (Hoboken). 2016 Jan 29;7(1):8-10. doi: 10.1002/cld.522. eCollection 2016 Jan.
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本文引用的文献
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Hepatoprotective and antiviral functions of silymarin components in hepatitis C virus infection.水飞蓟素成分在丙型肝炎病毒感染中的保肝和抗病毒作用
Hepatology. 2013 Mar;57(3):1262-71. doi: 10.1002/hep.26179.
2
Silibinin: an old drug in the high tech era of liver transplantation.
J Hepatol. 2013 Mar;58(3):409-11. doi: 10.1016/j.jhep.2012.11.030. Epub 2012 Nov 27.
3
Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial.水飞蓟素（奶蓟草）治疗干扰素治疗失败的慢性丙型肝炎患者肝脏疾病的效果：一项随机对照试验。
JAMA. 2012 Jul 18;308(3):274-82. doi: 10.1001/jama.2012.8265.
4
Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial.水飞蓟宾联合磷脂酰胆碱和维生素 E 治疗非酒精性脂肪性肝病的随机对照研究。
Free Radic Biol Med. 2012 May 1;52(9):1658-65. doi: 10.1016/j.freeradbiomed.2012.02.008. Epub 2012 Feb 15.
5
Intravenous silibinin as 'rescue treatment' for on-treatment non-responders to pegylated interferon/ribavirin combination therapy.静脉注射水飞蓟宾作为聚乙二醇化干扰素/利巴韦林联合治疗中治疗无应答者的“挽救疗法” 。
Antivir Ther. 2011;16(8):1327-33. doi: 10.3851/IMP1942.
6
Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis.吡格列酮、维生素 E 或安慰剂治疗非酒精性脂肪性肝炎。
N Engl J Med. 2010 May 6;362(18):1675-85. doi: 10.1056/NEJMoa0907929. Epub 2010 Apr 28.
7
Silibinin and related compounds are direct inhibitors of hepatitis C virus RNA-dependent RNA polymerase.水飞蓟宾及其相关化合物是丙型肝炎病毒 RNA 依赖的 RNA 聚合酶的直接抑制剂。
Gastroenterology. 2010 Mar;138(3):1112-22. doi: 10.1053/j.gastro.2009.11.053. Epub 2009 Dec 4.
8
Silibinin is a potent antiviral agent in patients with chronic hepatitis C not responding to pegylated interferon/ribavirin therapy.水飞蓟宾对于对聚乙二醇干扰素/利巴韦林治疗无反应的慢性丙型肝炎患者是一种有效的抗病毒药物。
Gastroenterology. 2008 Nov;135(5):1561-7. doi: 10.1053/j.gastro.2008.07.072. Epub 2008 Aug 3.
9
Antioxidant therapy for chronic hepatitis C after failure of interferon: results of phase II randomized, double-blind placebo controlled clinical trial.干扰素治疗失败后慢性丙型肝炎的抗氧化治疗：II期随机双盲安慰剂对照临床试验结果
World J Gastroenterol. 2007 Oct 28;13(40):5317-23. doi: 10.3748/wjg.v13.i40.5317.
10
Inhibition of T-cell inflammatory cytokines, hepatocyte NF-kappaB signaling, and HCV infection by standardized Silymarin.标准化水飞蓟素对T细胞炎性细胞因子、肝细胞NF-κB信号传导及丙型肝炎病毒感染的抑制作用
Gastroenterology. 2007 May;132(5):1925-36. doi: 10.1053/j.gastro.2007.02.038. Epub 2007 Feb 21.
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