National Institute for Public Health and the Environment (RIVM), Centre for Health Protection, Anthonie van Leeuwenhoeklaan 9, 3721 MA Bilthoven, The Netherlands.
Int J Environ Res Public Health. 2019 Apr 30;16(9):1525. doi: 10.3390/ijerph16091525.
This works aimed to assess the health risks of e-cigarette use to bystanders. The exhaled breath of 17 volunteers was collected while they were vaping, and the levels of nicotine, propylene glycol, glycerol, formaldehyde, acetaldehyde, acrolein, tobacco-specific nitrosamines (TSNAs), and heavy metals were analyzed. Increased levels of nicotine, propylene glycol, TSNAs and copper were found in the exhaled breath of the volunteers. From these measurements, bystander exposure was estimated for two different scenarios: (1) A non-ventilated car with two e-cigarette users and (2) a ventilated office with one e-cigarette user. Our results show that bystanders may experience irritation of the respiratory tract as a result of exposure to propylene glycol and glycerol. Systemic effects of nicotine should also be expected if nicotine-containing e-liquid is used, including palpitations, and an increase of the systolic blood pressure. Furthermore, due to the presence of TSNAs in some e-liquids, an increased risk of tumors could not be excluded for the 'car' scenario. While e-cigarette use can clearly have effects on the health of bystanders, the risks depend on the rate of ventilation, dimensions of the room, and vaping behavior of the e-cigarette user. The presence of TSNAs in e-liquids can be avoided, which will prevent the most serious effect identified (increased risk of tumors).
这项研究旨在评估电子烟对旁观者健康的风险。17 名志愿者在吸电子烟时呼出的气体被收集起来,分析其中尼古丁、丙二醇、甘油、甲醛、乙醛、丙烯醛、烟草特有的亚硝胺(TSNAs)和重金属的含量。志愿者呼出的气体中发现尼古丁、丙二醇、TSNAs 和铜的含量增加。根据这些测量结果,我们估算了两种不同情况下旁观者的暴露程度:(1)有两个电子烟使用者的不通风汽车;(2)有一个电子烟使用者的通风办公室。我们的研究结果表明,旁观者可能会因接触丙二醇和甘油而刺激呼吸道。如果使用含有尼古丁的电子烟液,还应预期会出现尼古丁的全身效应,包括心悸和收缩压升高。此外,由于一些电子烟液中存在 TSNAs,不能排除“汽车”场景中肿瘤风险增加的可能性。虽然电子烟的使用显然会对旁观者的健康产生影响,但风险取决于通风率、房间的尺寸和电子烟使用者的 vaping 行为。电子烟液中 TSNAs 的存在是可以避免的,这将防止识别出最严重的影响(肿瘤风险增加)。