Institute of Nuclear Chemistry and Technology, Food and Environmental Laboratory, Dorodna 16, 03-195 Warsaw, Poland.
Food Chem. 2019 Sep 15;292:129-133. doi: 10.1016/j.foodchem.2019.04.051. Epub 2019 Apr 16.
Arsenic and its inorganic species: As (III), As (V), dimethylarsenic acid (DMA) and monomethylarsenic acid (MMA) were determined in hypoallergenic formulas and grain porridges commercially available on Polish market, dedicated for infant 0-8 months. After quantitative extraction with 0.5% HNO, separation of individual species was performed by high performance liquid chromatography (HPLC), and their determination by neutron activation analysis (NAA) and inductively coupled plasma mass spectrometry (ICP-MS). Due to relatively low content of As in the analysed samples, it was only possible to determine DMA using the HPLC-ICP-MS mode. HPLC separation coupled with off-line determination by NAA enabled the determination of more extracted As species (especially inorganic) with good accuracy. Certified reference material (CRM) Rice Flour SRM 1568b (NIST) was used for the validation of both procedures.
三价砷（As (III)）、五价砷（As (V)）、二甲基砷酸（DMA）和一甲基砷酸（MMA）在波兰市场上销售的低变应原配方和谷物粥中进行了定量提取，这些产品是为 0-8 个月大的婴儿设计的。提取后用 0.5% HNO3 进行定量提取，采用高效液相色谱（HPLC）分离各形态，并用中子活化分析（NAA）和电感耦合等离子体质谱（ICP-MS）进行测定。由于分析样品中砷的含量相对较低，仅使用 HPLC-ICP-MS 模式才能测定 DMA。HPLC 分离与离线 NAA 测定相结合，可以很好地准确测定更多的提取砷形态（特别是无机砷）。使用认证参考物质（CRM）大米粉 SRM 1568b（NIST）对两种方法进行了验证。
