Singhania Renu, Sharma Nidhi, Vashisht Shashi, Dewan Taru
PGIMER, Dr. Ram Manohar Lohia Hospital. Delhi-110001.
Nepal J Ophthalmol. 2018 Jan;10(19):3-10. doi: 10.3126/nepjoph.v10i1.21661.
Chalazion is a common inflammatory mass lesion of eyelid. Incision and curettage is a conventional treatment but intralesional steroid is also a safe option for multiple chalazia and chalazion near lacrimal drainage system. So, we conducted an interventional study to compare the treatment outcomes of injection triamcinolone acetonide (TA) versus incision and curettage (I&C) in medium and large sized primary chalazion.
To compare the success rate of intralesional TA versus I&C for the treatment of medium and large sized primary chalazia.
An interventional study was carried out in 118 patients with primary chalazion. The patients were divided equally into two groups A and B of medium sized (3-7mm) and large sized chalazia (>7mm) respectively. Treatment modality either I&C or TA was decided in each group by randomization Cytological evaluation was done for each case and diagnosis other than chalazion was excluded. Main outcome measure was resolution in size more than 80%. Secondary outcome measure was correlation of cytological features with size, duration, success rate and complications.
Intralesional TA was found to be as effective as I&C in both the groups. In cytological analysis, we found that in large sized chalazia I&C is superior to TA in suppurating granuloma.
睑板腺囊肿是眼睑常见的炎性肿块病变。切开刮除术是一种传统治疗方法，但对于多发性睑板腺囊肿以及靠近泪道系统的睑板腺囊肿，病灶内注射类固醇也是一种安全的选择。因此，我们开展了一项干预性研究，以比较注射曲安奈德（TA）与切开刮除术（I&C）治疗中大型原发性睑板腺囊肿的疗效。
比较病灶内注射TA与I&C治疗中大型原发性睑板腺囊肿的成功率。
对118例原发性睑板腺囊肿患者进行了一项干预性研究。患者被平均分为A组和B组，分别为中型（3 - 7mm）和大型（>7mm）睑板腺囊肿。通过随机分组在每组中决定采用I&C或TA的治疗方式。对每个病例进行细胞学评估，并排除睑板腺囊肿以外的诊断。主要结局指标是大小缩小超过80%。次要结局指标是细胞学特征与大小、病程、成功率及并发症的相关性。
发现病灶内注射TA在两组中与I&C同样有效。在细胞学分析中，我们发现在大型睑板腺囊肿中，在化脓性肉芽肿方面I&C优于TA。
