Fukuda Atsushi, Morita Shinya, Nakamaru Yuji, Hoshino Kimiko, Fujiwara Keishi, Homma Akihiro
Department of Otolaryngology-Head and Neck Surgery, Hokkaido University, School of Medicine and Graduate School of Medicine, Hokkaido, Japan.
J Int Adv Otol. 2019 Apr;15(1):2-7. doi: 10.5152/iao.2019.5983.
The aim of the present study was to investigate the prognostic factors for short-term hearing outcomes of ossiculoplasty for primary pars flaccida cholesteatoma according to the European Academy of Otology and Neurotology/Japanese Otological Society (EAONO/JOS) and 2015 JOS staging systems.
A total of 34 patients with primary pars flaccida cholesteatoma who underwent one-stage tympanomastoidectomy with partial ossicular reconstruction using double cartilage block were included in the study. The postoperative pure-tone average air-bone gap (PTA-ABG) was calculated, and two criteria of successful hearing outcomes were defined as ≤10 and ≤20 dB. Patients were classified according to the EAONO/JOS and 2015 JOS staging systems. Cochran-Armitage test was used to statistically analyze staging, and Fisher's exact test was used to analyze other factors.
Successful hearing outcome with postoperative PTA-ABG ≤10 and ≤20 dB occurred in 23.5% and 55.9% of cases, respectively. When postoperative PTA-ABG ≤20 dB was defined as successful, the success rate significantly decreased with increase in EAONO/JOS stage, and S0 pathological status of the stapes (no involvement) was a significantly favorable predictive factor. When postoperative PTA-ABG ≤10 dB was regarded as successful, the significantly favorable predictive factors were S0 pathological status of the stapes and development of mastoid cells with MC2-3 (better developed cells).
Favorable prognostic factors for hearing outcomes of tympanomastoidectomy with partial ossicular reconstruction for primary pars flaccida cholesteatoma were low stage following the EAONO/JOS staging system and no stapes involvement and better development of mastoid cells following the 2015 JOS staging system.
本研究旨在根据欧洲耳科学与神经耳科学学会/日本耳科学会(EAONO/JOS)和2015年日本耳科学会分期系统,调查原发性松弛部胆脂瘤鼓室成形术短期听力结果的预后因素。
本研究纳入了34例接受一期鼓室乳突切除术并使用双软骨块进行部分听骨链重建的原发性松弛部胆脂瘤患者。计算术后纯音平均气骨导差(PTA-ABG),并将听力结果成功的两个标准定义为≤10 dB和≤20 dB。根据EAONO/JOS和2015年日本耳科学会分期系统对患者进行分类。采用 Cochr an-Armitage检验对分期进行统计学分析,采用Fisher精确检验分析其他因素。
术后PTA-ABG≤10 dB和≤20 dB的听力结果成功病例分别占23.5%和55.9%。当将术后PTA-ABG≤20 dB定义为成功时,成功率随EAONO/JOS分期增加而显著降低,镫骨S0病理状态(无受累)是显著有利的预测因素。当将术后PTA-ABG≤10 dB视为成功时,显著有利的预测因素是镫骨S0病理状态和具有MC2-3(发育较好的细胞)的乳突细胞发育。
原发性松弛部胆脂瘤鼓室乳突切除术并部分听骨链重建听力结果的有利预后因素是根据EAONO/JOS分期系统为低分期、无镫骨受累以及根据2015年日本耳科学会分期系统乳突细胞发育较好。