Chan Ruth, Yu Blanche, Leung Jason, Lee Jenny Shun-Wah, Woo Jean
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong.
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong; Jockey Club Centre for Osteoporosis Care and Control, The Chinese University of Hong Kong, Shatin, Hong Kong.
Clin Nutr ESPEN. 2019 Jun;31:38-47. doi: 10.1016/j.clnesp.2019.03.004. Epub 2019 Mar 23.
Studies examining the association between dietary patterns and inflammatory markers are limited, in particular among Chinese older adults.
We examined the association of various dietary patterns with serum high-sensitivity C-reactive protein (hsCRP) level in community-dwelling Chinese older adults, taking into account demographics and other lifestyle factors.
We conducted ordinal regression analyses using baseline data based on 1332 older men and 1314 older women of Chinese origin from a cohort study of bone health in Hong Kong. Baseline interviewer administered questionnaires included dietary intake estimation and dietary pattern generation from the food frequency questionnaire, as well as demographic and lifestyle factors. Serum hsCRP was measured using a commercially available enzyme-linked immunosorbent assay.
In men, higher serum hsCRP level was associated with lower Diet Quality Index-International (DQI-I) score, the Mediterranean-DASH Intervention for Neurodegenerative Delay diet (MIND) score, Okinawan diet score, "vegetables-fruits" pattern score, and lower adherence to the Mediterranean diet. In women, serum hsCRP level was not associated with any dietary patterns.
Our cross-sectional analyses suggest that various dietary patterns were associated with a lower serum hsCRP level in community-dwelling Chinese older adults, and these associations were only observed in older men.
研究饮食模式与炎症标志物之间关联的研究有限，尤其是在中国老年人中。
我们研究了社区居住的中国老年人中各种饮食模式与血清高敏C反应蛋白（hsCRP）水平之间的关联，并考虑了人口统计学和其他生活方式因素。
我们使用基于香港一项骨骼健康队列研究中1332名中国老年男性和1314名中国老年女性的基线数据进行有序回归分析。基线访谈者管理的问卷包括饮食摄入量估计、根据食物频率问卷生成的饮食模式，以及人口统计学和生活方式因素。血清hsCRP使用市售酶联免疫吸附测定法进行测量。
在男性中，较高的血清hsCRP水平与较低的国际饮食质量指数（DQI-I）得分、地中海-防治高血压饮食延缓神经退行性变饮食（MIND）得分、冲绳饮食得分、“蔬菜-水果”模式得分以及较低的地中海饮食依从性相关。在女性中，血清hsCRP水平与任何饮食模式均无关联。
我们的横断面分析表明，各种饮食模式与社区居住的中国老年人较低的血清hsCRP水平相关，且这些关联仅在老年男性中观察到。
