自闭症谱系障碍患儿及其家族中无自闭症患儿的姿势发展轨迹。
Trajectories of Posture Development in Infants With and Without Familial Risk for Autism Spectrum Disorder.
机构信息
Department of Psychiatry, UPMC Western Psychiatric Hospital, Merck Child Outpatient Clinic, University of Pittsburgh School of Medicine, 1011 Bingham St., Pittsburgh, PA, 15203, USA.
Department of Psychology, University of Pittsburgh, 3415 Sennott Square, 210 S. Bouquet St., Pittsburgh, PA, 15260, USA.
出版信息
J Autism Dev Disord. 2019 Aug;49(8):3257-3277. doi: 10.1007/s10803-019-04048-3.
This study investigated early posture development prospectively in infants at heightened (HR) vs. low risk (Low Risk; LR) for ASD. Fourteen HR infants diagnosed with ASD (HR-ASD), 17 HR infants with language delay (HR-LD), 29 HR infants with no diagnosis (HR-ND), and 25 LR infants were videotaped at home for 25 min during everyday activities and play at 6, 8, 10, 12, and 14 months. All postures were coded and the sustainment source was identified for supported postures. Relative to LR infants, HR-ASD infants and to a lesser extent HR-LD infants exhibited distinct postural trajectories that revealed slower development of more advanced postures. In addition, subtle differences in posture sustainment differentiated HR-ASD from HR-LD infants.
本研究前瞻性地研究了高风险（HR）和低风险（LR）自闭症谱系障碍（ASD）婴儿的早期姿势发展。对 14 名被诊断为 ASD 的高风险婴儿（HR-ASD）、17 名语言延迟的高风险婴儿（HR-LD）、29 名无诊断的高风险婴儿（HR-ND）和 25 名低风险婴儿进行了录像，在 6、8、10、12 和 14 个月时，在日常活动和游戏中在家中录像 25 分钟。对所有姿势进行编码，并确定支撑姿势的支撑源。与 LR 婴儿相比，HR-ASD 婴儿和在较小程度上的 HR-LD 婴儿表现出明显不同的姿势轨迹，表明更高级姿势的发育较慢。此外，姿势维持的细微差异将 HR-ASD 与 HR-LD 婴儿区分开来。
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