Department of Pharmacy, BRAC University, Dhaka, Bangladesh.
Department of Pharmacognosy, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, India.
Environ Sci Pollut Res Int. 2020 Jun;27(16):19151-19168. doi: 10.1007/s11356-019-05211-0. Epub 2019 May 11.
Nanotechnology is an emerging technology that deals with nanosized particles possessing crucial research roles and application. Disciplines like chemistry, biology, physics, engineering, materials science, and health sciences provide an accumulated knowledge of nanotechnology. Nonetheless, it has vast submissions precisely in biology, electronics, and medicine. Aimed at drug delivery system, nanoparticles are based on the mechanism of entrapment of the drugs or biomolecules into the interior structure of the particles; another mechanism could be that the drugs or the biomolecules can be absorbed onto the exterior surfaces of the particles. Currently, nanoparticles (NPs) are used in the delivery of drugs, proteins, genes, vaccines, polypeptides, nucleic acids, etc. In recent years, various applications of the drug delivery system via NPs have encountered an enormous position sector like pharmaceutical, medical, biological, and others. Considering the impact of NPs in drug delivery systems, this review focuses on the detailed profile of NPs, its impact on biology and medicine, and their commercialization prospects.
纳米技术是一门新兴技术，涉及具有关键研究作用和应用的纳米级颗粒。化学、生物学、物理学、工程学、材料科学和健康科学等学科为纳米技术提供了积累的知识。尽管如此，它在生物学、电子学和医学方面有着广泛的应用。纳米颗粒作为药物传递系统，其基于将药物或生物分子包埋到颗粒内部结构的机制；另一种机制是药物或生物分子可以被吸收到颗粒的外表面上。目前，纳米颗粒（NPs）已被用于药物、蛋白质、基因、疫苗、多肽、核酸等的传递。近年来，通过 NPs 进行药物传递系统的各种应用在制药、医疗、生物等领域都有了巨大的发展。考虑到 NPs 在药物传递系统中的影响，本综述重点介绍了 NPs 的详细概况、其对生物学和医学的影响及其商业化前景。
